SCHEMBL23113652

SCHEMBL23113652

NC(=O)c1cnc(N2CCCC(NC(=O)O)C2)nc1Nc1cc(Br)cc(C(=O)N2CCOCC2)c1

nearest known ligand 0.81

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ CAMK1D Q8IU85 12/20 0.81
▸ BTK Q06187 7/20 0.60
▸ LCK P06239 1/20 0.53
▸ JAK3 P52333 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30020786 0.90 CAMK1D (0.73) CAMK1DBTKLCK
SCHEMBL23113241 0.89 CAMK1D (1.00) CAMK1D
SCHEMBL23113242 0.89 CAMK1D (1.00) CAMK1D
SCHEMBL23113334 0.89 CAMK1D (0.83) CAMK1DBTKLCK
SCHEMBL28501115 0.87 CAMK1D (0.83) CAMK1DBTKLCKJAK3
SCHEMBL28499382 0.87 CAMK1D (0.81) CAMK1DBTK
SCHEMBL23113703 0.85 CAMK1D (0.83) CAMK1DBTKLCK
SCHEMBL23113260 0.82 CAMK1D (0.69) CAMK1D
SCHEMBL23113263 0.82 CAMK1D (0.69) CAMK1D
SCHEMBL23113585 0.82 CAMK1D (0.64) CAMK1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11530193-B2 Kinase inhibitors THE UNIVERSITY OF MANCHESTER (GB) 2022-12-20 — — US disclosed
EP-3793996-A1 KINASE INHIBITORS The University of Manchester (GB) 2021-03-24 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11530193-B2 Kinase inhibitors CAMKK2, CAMK1, CAMKK1 CAMK1D 5/4885BTK 1532/4885LCK 277/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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