Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCTL | Q9NXS2 | 2/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23115918 | 0.86 | QPCTL (0.41) | QPCTLCYP11B1CYP11B2P2RX7SMPD1 | |
| SCHEMBL23115689 | 0.85 | QPCTL (0.49) | QPCTLCYP11B1CYP11B2P2RX7KMT2A | |
| SCHEMBL23115717 | 0.83 | QPCTL (0.41) | QPCTLCYP11B1CYP11B2P2RX7SMPD1 | |
| SCHEMBL23115716 | 0.81 | QPCTL (0.41) | QPCTLCYP11B1CYP11B2P2RX7SMPD1 | |
| SCHEMBL23115986 | 0.78 | QPCTL (0.47) | QPCTLCYP11B1CYP11B2P2RX7KMT2A | |
| SCHEMBL23115865 | 0.74 | CYP11B1 (0.41) | QPCTLCYP11B1CYP11B2P2RX7KMT2A | |
| SCHEMBL20413799 | 0.72 | QPCTL (0.52) | QPCTLCYP11B1CYP11B2P2RX7KMT2A | |
| SCHEMBL23115852 | 0.69 | QPCTL (0.43) | QPCTLCYP11B1CYP11B2P2RX7CYP1A2 | |
| SCHEMBL23156356 | 0.69 | QPCTL (0.54) | QPCTLCYP11B1CYP11B2P2RX7KMT2A | |
| SCHEMBL17982169 | 0.69 | CYP11B2 (0.52) | QPCTLCYP11B1CYP11B2P2RX7KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12297190-B2 | Modulators of STING (stimulator of interferon genes) | PFIZER INC. (US) | 2025-05-13 | — | — | US | disclosed |
| EP-4526298-A1 | PYRAZOLE DERIVATIVES AS STING AGONISTS | F. Hoffmann-La Roche AG (CH) | 2025-03-26 | — | — | EP | disclosed |
| US-20250074913-A1 | PYRAZOLE DERIVATIVES AS STING AGONISTS | HOFFMANN-LA ROCHE INC. (US) | 2025-03-06 | — | — | US | disclosed |
| CN-119212989-A | Pyrazole derivatives as STING agonists | 豪夫迈·罗氏有限公司 | 2024-12-27 | — | — | CN | disclosed |
| WO-2023222644-A1 | PYRAZOLE DERIVATIVES AS STING AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-11-23 | — | — | WO | disclosed |
| WO-2023222644-A1 | PYRAZOLE DERIVATIVES AS STING AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-11-23 | — | — | WO | disclosed |
| EP-4034534-A1 | POLYHETEROCYCLIC MODULATORS OF STING (STIMULATOR OF INTERFERON GENES) | Pfizer Inc. (US) | 2022-08-03 | — | — | EP | disclosed |
| CN-114728946-A | Polyheterocyclic modulators of STING (stimulator of interferon genes) | 辉瑞公司 | 2022-07-08 | — | — | CN | disclosed |
| WO-2021059136-A1 | POLYHETEROCYCLIC MODULATORS OF STING (STIMULATOR OF INTERFERON GENES) | PFIZER INC. (US) | 2021-04-01 | — | — | WO | disclosed |
| WO-2021059136-A1 | POLYHETEROCYCLIC MODULATORS OF STING (STIMULATOR OF INTERFERON GENES) | PFIZER INC. (US) | 2021-04-01 | — | — | WO | disclosed |
| US-20210087180-A1 | Modulators of STING (Stimulator of Interferon Genes) | PFIZER INC. (US) | 2021-03-25 | — | — | US | disclosed |
| US-20210087180-A1 | Modulators of STING (Stimulator of Interferon Genes) | PFIZER INC. (US) | 2021-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12297190-B2 | Modulators of STING (stimulator of interferon genes) | STING1, IRF3, CGAS | QPCTL 2930/4885CYP11B1 974/4885CYP11B2 915/4885 |
| US-20250074913-A1 | PYRAZOLE DERIVATIVES AS STING AGONISTS | STING1, CGAS, MAVS | QPCTL 2542/4885CYP11B1 592/4885CYP11B2 845/4885 |
| US-20210087180-A1 | Modulators of STING (Stimulator of Interferon Genes) | STING1, IRF3, CGAS | QPCTL 2930/4885CYP11B1 974/4885CYP11B2 915/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.