Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 6/20 | 0.39 |
| ▸ | HTR2C | P28335 | 6/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19786102 | 0.84 | HTR2A (0.49) | ALDH1A1KDM4EHTR2AHTR2CHSD17B10 | |
| SCHEMBL23116646 | 0.70 | PRCP (0.48) | ALDH1A1KDM4EHTR2AHTR2CHSD17B10 | |
| SCHEMBL28466018 | 0.70 | CHRM2 (0.48) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL9615137 | 0.70 | HTR2A (0.55) | ALDH1A1KDM4ERAB9AHTR2AHTR2C | |
| SCHEMBL11282704 | 0.69 | ALDH1A1 (0.46) | ALDH1A1KDM4EHTR2AHTR2CHSD17B10 | |
| Hydrochloric Acid SCHEMBL9696491 | 0.69 | KDM4E (0.56) | ALDH1A1KDM4ERAB9AHTR2AHTR2C | |
| SCHEMBL11632574 | 0.68 | HTR6 (0.44) | ABCB1ABCG2ALDH1A1KDM4EHTR2A | |
| SCHEMBL797767 | 0.68 | PDE5A (0.52) | ALDH1A1KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL10959741 | 0.68 | L3MBTL1 (0.40) | ALDH1A1KDM4EHTR2AHTR2CHSD17B10 | |
| SCHEMBL11185140 | 0.67 | HSD17B10 (0.39) | ABCB1ABCG2ALDH1A1KDM4EHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3255044-B1 | DIAZA-BENZOFLUORANTHRENE COMPOUNDS | HARBIN PHARMACEUTICAL GROUP CO LTD GENERAL PHARMACEUTICAL FACTORY (CN) | 2020-04-01 | — | — | EP | disclosed |