Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH2 | P05091 | 3/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | F9 | P00740 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11087004 | 0.74 | ALDH1A1 (0.45) | TSHRALDH1A1KMT2A | |
| SCHEMBL914727 | 0.72 | MAOB (0.53) | MAOBMAPTTSHRNPSR1HPGD | |
| SCHEMBL23116705 | 0.72 | KDM4E (0.37) | MAPTHPGDHSD17B10KDM4EALDH1A1 | |
| SCHEMBL23116701 | 0.70 | TSHR (0.58) | MAPTTSHRNPSR1HPGDHSD17B10 | |
| SCHEMBL4137042 | 0.69 | KDM4E (0.44) | MAOBTSHRKDM4EMEN1KMT2A | |
| SCHEMBL13915050 | 0.68 | CYP11B1 (0.39) | MAOBHPGDHSD17B10KDM4EALDH1A1 | |
| SCHEMBL17168993 | 0.67 | MAPT (0.44) | MAPTTSHRNPSR1HPGDKDM4E | |
| Hydrochloric Acid SCHEMBL29289841 | 0.66 | MAPT (0.43) | MAPTTSHRNPSR1HPGDHSD17B10 | |
| SCHEMBL23116703 | 0.65 | MAOB (0.55) | MAOBMAPTTSHRHPGDHSD17B10 | |
| SCHEMBL17785124 | 0.65 | TSHR (0.50) | MAPTTSHRNPSR1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021047674-A1 | BICYCLIC COMPOUND THAT ACTS AS CRBN PROTEIN REGULATOR | 南京明德新药研发有限公司 | 2021-03-18 | — | — | WO | disclosed |