Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 5/20 | 0.49 |
| ▸ | MASP2 | O00187 | 3/20 | 0.48 |
| ▸ | ARG1 | P05089 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 3/20 | 0.40 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.39 |
| ▸ | ESRRG | P62508 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16967365 | 0.86 | GRIK1 (0.49) | GRIK1MASP2ARG1HRH3F2 | |
| SCHEMBL16967363 | 0.86 | GRIK1 (0.49) | GRIK1MASP2ARG1HRH3F2 | |
| SCHEMBL16967369 | 0.86 | GRIK1 (0.49) | GRIK1MASP2ARG1HRH3F2 | |
| SCHEMBL23273781 | 0.86 | GRIK1 (0.49) | GRIK1MASP2ARG1HRH3F2 | |
| SCHEMBL3182372 | 0.86 | GRIK1 (0.49) | GRIK1MASP2ARG1HRH3F2 | |
| Hydrochloric Acid SCHEMBL25363248 | 0.85 | GRIK1 (0.50) | GRIK1MASP2ARG1HRH3F2 | |
| SCHEMBL29352179 | 0.84 | GRIK1 (0.50) | GRIK1MASP2ARG1HRH3F2 | |
| SCHEMBL11242285 | 0.84 | GRIK1 (0.52) | GRIK1MASP2ARG1HRH3F2 | |
| SCHEMBL11242281 | 0.84 | GRIK1 (0.52) | GRIK1MASP2ARG1HRH3F2 | |
| SCHEMBL19599284 | 0.84 | GRIK1 (0.47) | GRIK1MASP2ARG1HRH3F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113967258-B | FAP-activated therapeutic agents and related uses | 塔夫茨大学信托人 | 2024-07-02 | — | — | CN | disclosed |
| EP-4135738-A2 | METHOD OF TREATING CORONAVIRUS INFECTIONS | Cohbar Inc. (US) | 2023-02-22 | — | — | EP | disclosed |
| US-11302421-B2 | Data storage using peptides | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2022-04-12 | — | — | US | disclosed |
| CN-114269367-A | Therapeutic peptides | 科巴公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-113967258-A | FAP-activated therapeutics and uses related thereto | 塔夫茨大学信托人 | 2022-01-25 | — | — | CN | disclosed |
| CN-113956325-A | FAP-activated therapeutics and uses related thereto | 塔夫茨大学信托人 | 2022-01-21 | — | — | CN | disclosed |
| US-20210090688-A1 | Data storage using peptides | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2021-03-25 | — | — | US | disclosed |