SCHEMBL29352179 — predicted protein targets

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	GRIK1	P39086	5/20	0.50

▸	F2	P00734	7/20	0.43

▸	HRH3	Q9Y5N1	2/20	0.41

▸	ARG1	P05089	1/20	0.39

▸	MASP2	O00187	2/20	0.38

▸	CYP1A2	P05177	1/20	0.36

▸	CYP2C19	P33261	1/20	0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL11247986	0.88	F2 (0.51)	GRIK1F2HRH3MASP2
SCHEMBL11247984	0.88	F2 (0.51)	GRIK1F2HRH3MASP2
SCHEMBL23118028	0.84	GRIK1 (0.49)	GRIK1F2HRH3ARG1MASP2
SCHEMBL20746440	0.83	GRIK1 (0.53)	GRIK1F2HRH3ARG1
SCHEMBL29350039	0.83	GRIK1 (0.53)	GRIK1F2HRH3ARG1
Hydrochloric Acid SCHEMBL30405343	0.82	GRIK1 (0.54)	GRIK1F2HRH3ARG1
SCHEMBL3182082	0.81	EED (0.53)	GRIK1CYP1A2
SCHEMBL1706921	0.81	HRH3 (0.54)	GRIK1F2HRH3ARG1MASP2
SCHEMBL22536533	0.81	HRH3 (0.54)	GRIK1F2HRH3ARG1MASP2
SCHEMBL19292680	0.81	HRH3 (0.54)	GRIK1F2HRH3ARG1MASP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-113967258-A	FAP-activated therapeutics and uses related thereto	塔夫茨大学信托人	2022-01-25	—	—	CN	disclosed
CN-113956325-A	FAP-activated therapeutics and uses related thereto	塔夫茨大学信托人	2022-01-21	—	—	CN	disclosed