Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | RBBP5 | Q15291 | 2/20 | 0.45 |
| ▸ | DPY30 | Q9C005 | 2/20 | 0.45 |
| ▸ | ASH2L | Q9UBL3 | 2/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 7/20 | 0.44 |
| ▸ | EZH2 | Q15910 | 3/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | NNMT | P40261 | 3/20 | 0.38 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.38 |
| ▸ | DOT1L | Q8TEK3 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23120346 | 1.00 | WDR5 (0.45) | WDR5KMT2ARBBP5DPY30ASH2L | |
| SCHEMBL23120343 | 0.95 | WDR5 (0.44) | WDR5KMT2ARBBP5DPY30ASH2L | |
| SCHEMBL23120342 | 0.95 | WDR5 (0.44) | WDR5KMT2ARBBP5DPY30ASH2L | |
| SCHEMBL31713909 | 0.94 | WDR5 (0.50) | WDR5KMT2ARBBP5DPY30ASH2L | |
| SCHEMBL23120190 | 0.94 | WDR5 (0.50) | WDR5KMT2ARBBP5DPY30ASH2L | |
| SCHEMBL23120194 | 0.94 | WDR5 (0.50) | WDR5KMT2ARBBP5DPY30ASH2L | |
| SCHEMBL24508073 | 0.90 | PRMT5 (0.43) | WDR5KMT2ARBBP5DPY30ASH2L | |
| SCHEMBL29743107 | 0.90 | PRMT5 (0.43) | WDR5KMT2ARBBP5DPY30ASH2L | |
| SCHEMBL23120370 | 0.88 | EZH2 (0.42) | WDR5KMT2ARBBP5DPY30ASH2L | |
| SCHEMBL23120333 | 0.84 | NNMT (0.38) | WDR5KMT2ARBBP5DPY30ASH2L |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021053158-A1 | NOVEL HISTONE METHYLTRANSFERASE INHIBITORS | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2021-03-25 | — | — | WO | claimed |
| WO-2021053158-A1 | NOVEL HISTONE METHYLTRANSFERASE INHIBITORS | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2021-03-25 | — | — | WO | disclosed |