SCHEMBL2312150

SCHEMBL2312150

O=C(O)C[C@@H](CCc1ccccc1)NC(=O)Cc1cccc(Cl)c1.O=C(O)C[C@H](Cc1ccc(C(F)(F)F)cc1)NC(=O)Cc1ccccc1Cl

nearest known ligand 0.78

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FFAR2 O15552 12/20 0.78
MMEL1 Q495T6 2/20 0.47
MME P08473 3/20 0.46
KCNJ5 P48544 1/20 0.45
KCNJ3 P48549 1/20 0.45
PIN1 Q13526 1/20 0.43
LMNA P02545 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2317648 0.88 FFAR2 (1.00) FFAR2MMEL1MMEPIN1
SCHEMBL2312533 0.88 FFAR2 (1.00) FFAR2MMEL1MMEPIN1
SCHEMBL2318414 0.88 FFAR2 (1.00) FFAR2MMEL1MMEPIN1
SCHEMBL30355048 0.88 FFAR2 (1.00) FFAR2MMEL1MMEPIN1
SCHEMBL2314448 0.87 FFAR2 (0.69) FFAR2MMEL1MMEKCNJ5KCNJ3
SCHEMBL2314458 0.87 FFAR2 (0.69) FFAR2MMEL1MMEKCNJ5KCNJ3
SCHEMBL2312985 0.83 FFAR2 (0.62) FFAR2MMEL1MMEKCNJ5KCNJ3
SCHEMBL2312990 0.83 FFAR2 (0.62) FFAR2MMEL1MMEKCNJ5KCNJ3
SCHEMBL2319342 0.82 FFAR2 (0.72) FFAR2MMEL1MMELMNA
SCHEMBL2319336 0.82 FFAR2 (0.72) FFAR2MMEL1MMELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011092284-A1 NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS EUROSCREEN S.A. (BE) 2011-08-04 WO claimed