SCHEMBL2319336

SCHEMBL2319336

O=C(O)C[C@H](Cc1ccc(C(F)(F)F)cc1)NC(=O)Cc1ccc(Cl)cc1Cl

nearest known ligand 0.72

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FFAR2 O15552 5/20 0.72
MMEL1 Q495T6 4/20 0.52
MME P08473 7/20 0.50
LMNA P02545 1/20 0.48
CNR2 P34972 1/20 0.48
PRSS1 P07477 1/20 0.48
PRSS2 P07478 1/20 0.48
PRSS3 P35030 1/20 0.48
EEF2K O00418 1/20 0.46
PPARG P37231 1/20 0.45
PPARA Q07869 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2319342 1.00 FFAR2 (0.72) FFAR2MMEL1MMELMNACNR2
SCHEMBL2312968 0.90 MME (0.60) FFAR2MMEL1MMEPRSS1PRSS2
SCHEMBL2312962 0.90 MME (0.60) FFAR2MMEL1MMEPRSS1PRSS2
SCHEMBL2314458 0.87 FFAR2 (0.69) FFAR2MMEL1MMECNR2
SCHEMBL2314448 0.87 FFAR2 (0.69) FFAR2MMEL1MMECNR2
SCHEMBL2319964 0.87 FFAR2 (0.78) FFAR2MMEL1MMECNR2PPARG
SCHEMBL2314839 0.87 FFAR2 (0.78) FFAR2MMEL1MMECNR2PPARG
SCHEMBL2314845 0.87 FFAR2 (0.78) FFAR2MMEL1MMECNR2PPARG
SCHEMBL2318414 0.84 FFAR2 (1.00) FFAR2MMEL1MMECNR2
SCHEMBL2317648 0.84 FFAR2 (1.00) FFAR2MMEL1MMECNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011092284-A1 NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS EUROSCREEN S.A. (BE) 2011-08-04 WO claimed