SCHEMBL2312167

SCHEMBL2312167

O=C(O)C[C@H](Cc1ccc(C(F)(F)F)cc1)NC(=O)Cc1ccccc1C(F)(F)F

nearest known ligand 0.64

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FFAR2 O15552 4/20 0.64
MME P08473 6/20 0.59
EPHX2 P34913 5/20 0.47
PPARG P37231 4/20 0.47
CNR2 P34972 2/20 0.47
PIN1 Q13526 1/20 0.47
PSMB5 P28074 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2312174 1.00 FFAR2 (0.64) FFAR2MMEEPHX2PPARGCNR2
SCHEMBL2316497 0.90 FFAR2 (0.60) FFAR2MMEEPHX2PPARGCNR2
SCHEMBL2316507 0.90 FFAR2 (0.60) FFAR2MMEEPHX2PPARGCNR2
SCHEMBL2314448 0.88 FFAR2 (0.69) FFAR2MMECNR2PIN1
SCHEMBL2314458 0.88 FFAR2 (0.69) FFAR2MMECNR2PIN1
SCHEMBL2364855 0.87 FFAR2 (0.77) FFAR2MMECNR2PIN1
SCHEMBL2364853 0.87 FFAR2 (0.77) FFAR2MMECNR2PIN1
SCHEMBL2316287 0.86 MME (0.54) FFAR2MMEEPHX2PPARGPSMB5
SCHEMBL2316296 0.86 MME (0.54) FFAR2MMEEPHX2PPARGPSMB5
SCHEMBL2312671 0.85 FFAR2 (0.74) FFAR2MMECNR2PIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011092284-A1 NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS EUROSCREEN S.A. (BE) 2011-08-04 WO claimed