Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.48 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2316287 | 1.00 | MME (0.54) | MMEMEN1KMT2AFFAR2PSMB5 | |
| SCHEMBL2312174 | 0.86 | FFAR2 (0.64) | MMEFFAR2PSMB5EPHX2PPARG | |
| SCHEMBL2312167 | 0.86 | FFAR2 (0.64) | MMEFFAR2PSMB5EPHX2PPARG | |
| SCHEMBL2316507 | 0.85 | FFAR2 (0.60) | MMEFFAR2PSMB5EPHX2PPARG | |
| SCHEMBL2316497 | 0.85 | FFAR2 (0.60) | MMEFFAR2PSMB5EPHX2PPARG | |
| SCHEMBL2315703 | 0.84 | KMT2A (0.53) | MMEMEN1KMT2AFFAR2LMNA | |
| SCHEMBL2317287 | 0.84 | MEN1 (0.56) | MMEMEN1KMT2AFFAR2LMNA | |
| SCHEMBL2317282 | 0.84 | MEN1 (0.56) | MMEMEN1KMT2AFFAR2LMNA | |
| SCHEMBL2315692 | 0.84 | KMT2A (0.53) | MMEMEN1KMT2AFFAR2LMNA | |
| SCHEMBL2315472 | 0.84 | MEN1 (0.70) | MMEMEN1KMT2AFFAR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092284-A1 | NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS | EUROSCREEN S.A. (BE) | 2011-08-04 | — | — | WO | claimed |