SCHEMBL231222

SCHEMBL231222

O=C(O)c1cc([N+](=O)[O-])ccc1Cl

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.63
RORC P51449 4/20 0.63
CYP3A4 P08684 3/20 0.63
MAPT P10636 3/20 0.63
MEN1 O00255 3/20 0.63
TP53 P04637 3/20 0.63
MAPK1 P28482 2/20 0.63
PPARG P37231 2/20 0.63
SMN1; SMN2 Q16637 2/20 0.63
LMNA P02545 1/20 0.63
CYP1A2 P05177 1/20 0.63
CYP2D6 P10635 1/20 0.63
CYP2C9 P11712 1/20 0.63
PKM P14618 1/20 0.63
TSHR P16473 1/20 0.63
NFKB1 P19838 1/20 0.63
CYP2C19 P33261 1/20 0.63
THPO P40225 1/20 0.63
MTOR P42345 1/20 0.63
PMP22 Q01453 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6202524 0.98 KMT2A (0.61) KMT2ARORCCYP3A4MAPTMEN1
SCHEMBL8450902 0.98 KMT2A (0.61) KMT2ARORCCYP3A4MAPTMEN1
SCHEMBL6392429 0.98 KMT2A (0.61) KMT2ARORCCYP3A4MAPTMEN1
SCHEMBL27637460 0.91 KMT2A (0.55) KMT2ARORCCYP3A4MAPTMEN1
SCHEMBL10953243 0.87 HSD17B10 (0.62) KMT2ARORCCYP3A4MAPTMEN1
SCHEMBL9074113 0.85 RORC (0.53) KMT2ARORCCYP3A4MAPTMEN1
SCHEMBL398463 0.85 HSD17B10 (0.60) KMT2ARORCCYP3A4MAPTMEN1
SCHEMBL231457 0.85 KMT2A (0.72) KMT2ACYP3A4MAPTMAPK1SMN1; SMN2
SCHEMBL1789120 0.84 KMT2A (0.75) KMT2ARORCCYP3A4MAPTMEN1
SCHEMBL8447120 0.84 KMT2A (0.70) KMT2ACYP3A4MAPTMAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1331 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
CN-119930435-A Preparation method of mesalamine intermediate 珠海润都制药股份有限公司 2025-05-06 CN claimed
CN-119569654-A 9-Aminoacridine compound with multi-electron-withdrawing substituent, and preparation method and application thereof 郑州大学 2025-03-07 CN claimed
WO-2024167565-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS PURDUE RESEARCH FOUNDATION (US) 2024-08-15 WO claimed
CN-116199571-A Method for controlling content of organic carboxylic acid in synthesis process of benzophenone photoinitiator 宜都市友源实业有限公司 2023-06-02 CN claimed
CN-112125926-B Novel chlorine-containing carboxylic acid metal complex, preparation method and application thereof 广西民族师范学院 2023-04-25 CN claimed
CN-110133118-B Method for determining related substances of mesalazine enteric sustained-release tablets 重庆健能医药开发有限公司 2022-03-11 CN claimed
CN-109799292-B Mesalazine enema related substance determination method 重庆健能医药开发有限公司 2022-02-22 CN claimed
CN-214131604-U Double-kettle type continuous nitration reaction device for producing 2-chloro-5-nitrobenzoic acid 武汉伯业科技发展有限公司 2021-09-07 CN claimed
CN-213791646-U Temperature-adjustable reaction device for producing 2-chloro-5-nitrobenzoic acid 武汉伯业科技发展有限公司 2021-07-27 CN claimed
EP-0780376-A1 2-Acylamino-9-aryl-acridines, process for their preparation and light-sensitive compositions containing them HOECHST AKTIENGESELLSCHAFT (DE) 1997-06-25 EP claimed
EP-0751768-A1 ANTI-VIRAL AND ANTI-CANCER AGENTS RADOPATH LIMITED (GB) 1997-01-08 EP claimed
WO-1996029067-A1 ANTI-VIRAL AND ANTI-CANCER AGENTS RADOPATH LIMITED (GB) 1996-09-26 WO claimed
EP-0700287-A1 ARYLATING MEDICAMENTS RADOPATH LIMITED (GB) 1996-03-13 EP claimed
EP-0677292-A1 Anti-viral and anti-cancer agents RADOPATH LIMITED (GB) 1995-10-18 EP claimed
WO-1995024897-A1 ANTI-VIRAL AND ANTI-CANCER AGENTS RADOPATH LIMITED (GB) 1995-09-21 WO claimed
WO-1994027584-A2 ARYLATING MEDICAMENTS RADOPATH LIMITED (GB) 1994-12-08 WO claimed
US-5277790-A Non-cyanide electroplating solution for gold or alloys thereof TECHNIC INCORPORATED (US) 1994-01-11 US claimed
US-4179476-A Semi-continuous process for obtaining amino compounds CIBA-GEIGY CORPORATION (US) 1979-12-18 US claimed
US-3936509-A Process for separating dimethyl naphthalenes comprising 2,6-dimethyl naphthalenes as main component TEIJIN LIMITED (JA) 1976-02-03 US claimed