Sugi Predict

Sugi Predict / Compounds / SCHEMBL398463

SCHEMBL398463

SCHEMBL398463

O=C(Cl)c1cc([N+](=O)[O-])ccc1Cl

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HSD17B10 Q99714 1/20 0.60
▸ RORC P51449 7/20 0.59
▸ KMT2A Q03164 5/20 0.59
▸ SMN1; SMN2 Q16637 3/20 0.59
▸ MEN1 O00255 3/20 0.59
▸ CYP3A4 P08684 2/20 0.59
▸ MAPK1 P28482 2/20 0.59
▸ PPARG P37231 2/20 0.59
▸ LMNA P02545 2/20 0.59
▸ TP53 P04637 1/20 0.59
▸ CYP1A2 P05177 1/20 0.59
▸ CYP2D6 P10635 1/20 0.59
▸ MAPT P10636 1/20 0.59
▸ CYP2C9 P11712 1/20 0.59
▸ PKM P14618 1/20 0.59
▸ TSHR P16473 1/20 0.59
▸ NFKB1 P19838 1/20 0.59
▸ CYP2C19 P33261 1/20 0.59
▸ THPO P40225 1/20 0.59
▸ MTOR P42345 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methane SCHEMBL28180987 0.98 HSD17B10 (0.58) HSD17B10RORCKMT2ASMN1; SMN2MEN1
SCHEMBL10953243 0.87 HSD17B10 (0.62) HSD17B10RORCKMT2ASMN1; SMN2MEN1
SCHEMBL752917 0.85 KMT2A (0.72) HSD17B10KMT2ASMN1; SMN2MEN1MAPK1
SCHEMBL231222 0.85 KMT2A (0.63) HSD17B10RORCKMT2ASMN1; SMN2MEN1
SCHEMBL10694655 0.85 ALDH1A1 (0.57) HSD17B10RORCKMT2ASMN1; SMN2MEN1
SCHEMBL1803851 0.84 HSD17B10 (0.58) HSD17B10RORCKMT2ASMN1; SMN2MEN1
SCHEMBL1762503 0.84 KMT2A (0.61) HSD17B10RORCKMT2ASMN1; SMN2MEN1
SCHEMBL8450902 0.84 KMT2A (0.61) HSD17B10RORCKMT2ASMN1; SMN2MEN1
SCHEMBL6392429 0.84 KMT2A (0.61) HSD17B10RORCKMT2ASMN1; SMN2MEN1
Hydrochloric Acid SCHEMBL6202524 0.84 KMT2A (0.61) HSD17B10RORCKMT2ASMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 417 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116178203-B Polyimide containing amide bond and benzonorbornane structure and preparation method thereof 南昌大学 2025-02-14 — — CN claimed
CN-116178203-A Polyimide containing amide bond and benzonorbornane structure and preparation method thereof 南昌大学 2023-05-30 — — CN claimed
CN-106699570-B Synthesis method of (2-chloro-5-iodophenyl) (4-fluorophenyl) ketone 山东铂源药业有限公司 2020-04-21 — — CN claimed
CN-106699570-A Synthesis method for (2-chloro-5-iodophenyl)(4-fluorophenyl)ketone 山东铂源药业有限公司 2017-05-24 — — CN claimed
CN-106366000-A Preparation method of 2-chloro-5-nitrobenzophenone 枣阳凤泽精细化工有限公司 2017-02-01 — — CN claimed
CN-100386305-C Process for preparing 2-chloro-5-nitro phenyl -4'-methoxy benzophenone SHANGHAI CHEMICAL REAGENT RES (CN) 2008-05-07 — — CN claimed
CN-1721388-A Process for preparing 2-chloro-5-nitro phenyl -4'-methoxy benzophenone SHANGHAI CHEMICAL REAGENT RES (CN) 2006-01-18 — — CN claimed
US-20050004377-A1 Methods for producing amino substituted chromanes and intermediates therefor MILLENNIUM PHARMACEUTICALS, INC. 2005-01-06 — — US claimed
EP-1284972-A1 METHODS FOR PRODUCING AMINO SUBSTITUTED CHROMANES AND INTERMEDIATES THEREFOR COR THERAPEUTICS, INC. (US) 2003-02-26 — — EP claimed
WO-2001087872-A1 METHODS FOR PRODUCING AMINO SUBSTITUTED CHROMANES AND INTERMEDIATES THEREFOR MILLENIUM PHARMACEUTICALS, INC. (US) 2001-11-22 — — WO claimed
US-6262277-B1 IN MEDICINE FOR PROPHYLAXIS AND THERAPY OF HYPERLIPIDEMIC CONDITIONS SUCH AS THOSE ASSOCIATED WITH ATHEROSCLEROSIS OR HYPERCHOLESTEROLEMIA, IN MAMMALS G.D. SEARLE AND COMPANY 2001-07-17 — — US claimed
JP-56067309-A — — None — — JP disclosed
US-20260125351-A1 COMPOUND FOR INDUCING EXPRESSION OF ANTI-AGING GENE KLOTHO AND USE THEREOF KLOTHO SCIENCES (KR) 2026-05-07 — — US disclosed
EP-4644362-A1 CYCLOPROPYLAMIDE COMPOUNDS AGAINST PARASITES IN FISH Intervet International B.V. (NL) 2025-11-05 — — EP disclosed
US-20250228239-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-07-17 — — US disclosed
EP-0004279-A1 Process for the preparation of 4-pyridone-3-carboxylic acids, 1-cyclopropyl-4-pyridone-3-carboxylic acid derivatives and medicines containing them BAYER AG (DE) 1979-10-03 — — EP disclosed
US-4052444-A DIAZO COUPLERS FOR MONOAZO DYES HOECHST AKTIENGESELLSCHAFT (DT) 1977-10-04 — — US disclosed
US-4026709-A Color photographic recording material CIBA-GEIGY AG (CH) 1977-05-31 — — US disclosed
US-3984432-A PHOSPHONIC ACID AND PHOSPHORIC ACID DERIVATIVES CIBA-GEIGY AG (CH) 1976-10-05 — — US disclosed
US-3971741-A DISPERSION PIGMENTS BAYER AKTIENGESELLSCHAFT (DT) 1976-07-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260125351-A1 COMPOUND FOR INDUCING EXPRESSION OF ANTI-AGING GENE KLOTHO AND USE THEREOF GLA, CTSA, KLF5 HSD17B10 724/4885RORC 2988/4885KMT2A 571/4885
US-20050004377-A1 Methods for producing amino substituted chromanes and intermediates therefor FAR1, GOT1, WEE1 HSD17B10 693/4885RORC 4443/4885KMT2A 3244/4885
US-20250228239-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO ACHE, DDT, MLYCD HSD17B10 2420/4885RORC 2599/4885KMT2A 2615/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.