Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | RAPGEF4 | Q8WZA2 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | S100B | P04271 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1115815 | 0.96 | RAPGEF4 (0.47) | ALDH1A1RAPGEF4TSHRHTTMEN1 | |
| SCHEMBL1115839 | 0.96 | RAPGEF4 (0.47) | ALDH1A1RAPGEF4TSHRHTTMEN1 | |
| SCHEMBL31405486 | 0.92 | RAPGEF4 (0.47) | ALDH1A1RAPGEF4TSHRHTTMEN1 | |
| SCHEMBL682063 | 0.89 | ALDH1A1 (0.46) | ALDH1A1RAPGEF4TSHRCYP1A2CYP3A4 | |
| SCHEMBL12018763 | 0.89 | ALDH1A1 (0.46) | ALDH1A1RAPGEF4TSHRCYP1A2CYP3A4 | |
| SCHEMBL13174556 | 0.85 | ALDH1A1 (0.45) | ALDH1A1RAPGEF4TSHRHTTMEN1 | |
| SCHEMBL12440938 | 0.85 | ALDH1A1 (0.45) | ALDH1A1RAPGEF4TSHRHTTMEN1 | |
| SCHEMBL1116041 | 0.85 | RAPGEF4 (0.40) | ALDH1A1RAPGEF4TSHR | |
| SCHEMBL2314652 | 0.85 | ALDH1A1 (0.40) | ALDH1A1RAPGEF4HTTIGF1RTDP1 | |
| SCHEMBL15304825 | 0.85 | RAPGEF4 (0.40) | ALDH1A1RAPGEF4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2000855-B1 | Image bearing member, method of manufacturing the same, image formation method, image forming apparatus and process cartridge | RICOH CO LTD (JP) | 2011-08-03 | — | — | EP | disclosed |
| US-20080304867-A1 | Image bearing member, method of manufacturing the same, image formation method, image forming apparatus and process cartridge | RICOH COMPANY, LTD. | 2008-12-11 | — | — | US | disclosed |
| EP-2000855-A1 | Image bearing member, method of manufacturing the same, image formation method, image forming apparatus and process cartridge | Ricoh Company, Ltd. (JP) | 2008-12-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080304867-A1 | Image bearing member, method of manufacturing the same, image formation method, image forming apparatus and process cartridge | KDM1A, C9, JMJD6 | ALDH1A1 1243/4885RAPGEF4 3290/4885TSHR 4581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.