Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.49 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 8/20 | 0.45 |
| ▸ | NPC1 | O15118 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22074361 | 0.82 | ALDH1A1 (0.59) | TRPM8FKBP1AMAPTRAB9ANPC1 | |
| SCHEMBL20902900 | 0.77 | TRPM8 (0.52) | TRPM8FKBP1AMAPTRAB9ANPC1 | |
| SCHEMBL20363079 | 0.75 | TRPM8 (0.63) | TRPM8MAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL20773543 | 0.74 | TRPM8 (0.76) | TRPM8FKBP1AMAPTRAB9ANPC1 | |
| SCHEMBL2729724 | 0.73 | TRPM8 (0.68) | TRPM8 | |
| SCHEMBL2729834 | 0.73 | TRPM8 (0.67) | TRPM8FKBP1AMAPTRAB9ANPC1 | |
| SCHEMBL2729507 | 0.73 | TRPM8 (0.67) | TRPM8MAPTALDH1A1KDM4EGAA | |
| SCHEMBL20902963 | 0.72 | TRPM8 (0.51) | TRPM8FKBP1AMAPTRAB9ANPC1 | |
| SCHEMBL5533520 | 0.70 | ALDH1A1 (0.66) | FKBP1AMAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL8389779 | 0.69 | MAPT (0.62) | FKBP1AMAPTRAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10953007-B2 | Compounds useful as modulators of TRPM8 | FIRMENICH INCORPORATED (US) | 2021-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10953007-B2 | Compounds useful as modulators of TRPM8 | TRPM8, TRPM7, TRPM6 | TRPM8 1/4885FKBP1A 851/4885MAPT 1079/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.