Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 3/20 | 0.66 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.56 |
| ▸ | MME | P08473 | 1/20 | 0.53 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2320363 | 0.87 | PIN1 (0.69) | PIN1FFAR2MMEMEN1MAPT | |
| SCHEMBL2320355 | 0.87 | PIN1 (0.69) | PIN1FFAR2MMEMEN1MAPT | |
| SCHEMBL2312985 | 0.87 | FFAR2 (0.62) | PIN1FFAR2MMEMEN1MAPT | |
| SCHEMBL2312990 | 0.87 | FFAR2 (0.62) | PIN1FFAR2MMEMEN1MAPT | |
| SCHEMBL2312583 | 0.86 | FFAR2 (0.72) | PIN1FFAR2MMEMEN1MAPT | |
| SCHEMBL2312580 | 0.86 | FFAR2 (0.72) | PIN1FFAR2MMEMEN1MAPT | |
| SCHEMBL2320231 | 0.85 | PIN1 (0.74) | PIN1FFAR2MMEMEN1MAPT | |
| SCHEMBL2315266 | 0.85 | PIN1 (0.74) | PIN1FFAR2MMEMEN1MAPT | |
| SCHEMBL2320240 | 0.85 | PIN1 (0.74) | PIN1FFAR2MMEMEN1MAPT | |
| SCHEMBL2314866 | 0.85 | PIN1 (0.74) | PIN1FFAR2MMEMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092284-A1 | NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS | EUROSCREEN S.A. (BE) | 2011-08-04 | — | — | WO | claimed |