Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | CCR3 | P51677 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2317287 | 0.85 | MEN1 (0.56) | MMEKMT2AMEN1MAPTLMNA | |
| SCHEMBL2315703 | 0.85 | KMT2A (0.53) | MMEKMT2AMEN1MAPTLMNA | |
| SCHEMBL2317282 | 0.85 | MEN1 (0.56) | MMEKMT2AMEN1MAPTLMNA | |
| SCHEMBL2315692 | 0.85 | KMT2A (0.53) | MMEKMT2AMEN1MAPTLMNA | |
| SCHEMBL2315478 | 0.84 | MEN1 (0.70) | MMEKMT2AMEN1ITGB3ITGA2B | |
| SCHEMBL2315472 | 0.84 | MEN1 (0.70) | MMEKMT2AMEN1ITGB3ITGA2B | |
| SCHEMBL2315652 | 0.84 | MME (0.54) | MMEKMT2AMEN1LMNA | |
| SCHEMBL2315641 | 0.84 | MME (0.54) | MMEKMT2AMEN1LMNA | |
| SCHEMBL2316267 | 0.84 | MEN1 (0.57) | MMEKMT2AMEN1MAPTHTT | |
| SCHEMBL2316276 | 0.84 | MEN1 (0.57) | MMEKMT2AMEN1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092284-A1 | NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS | EUROSCREEN S.A. (BE) | 2011-08-04 | — | — | WO | claimed |