Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MME | P08473 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2317287 | 1.00 | MEN1 (0.56) | MEN1KMT2AMMEMAPTALDH1A1 | |
| SCHEMBL2316489 | 0.87 | MME (0.51) | MEN1KMT2AMMELMNAMMEL1 | |
| SCHEMBL2316483 | 0.87 | MME (0.51) | MEN1KMT2AMMELMNAMMEL1 | |
| SCHEMBL2315692 | 0.87 | KMT2A (0.53) | MEN1KMT2AMMEMAPTCYP3A4 | |
| SCHEMBL2315703 | 0.87 | KMT2A (0.53) | MEN1KMT2AMMEMAPTCYP3A4 | |
| SCHEMBL2316457 | 0.86 | LMNA (0.55) | MEN1KMT2AMMEMAPTALDH1A1 | |
| SCHEMBL2316474 | 0.86 | LMNA (0.55) | MEN1KMT2AMMEMAPTALDH1A1 | |
| SCHEMBL2315472 | 0.86 | MEN1 (0.70) | MEN1KMT2AMMEMAPTALDH1A1 | |
| SCHEMBL2315478 | 0.86 | MEN1 (0.70) | MEN1KMT2AMMEMAPTALDH1A1 | |
| SCHEMBL2312765 | 0.85 | MME (0.53) | MEN1KMT2AMMEMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092284-A1 | NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS | EUROSCREEN S.A. (BE) | 2011-08-04 | — | — | WO | claimed |
| WO-2011092284-A1 | NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS | EUROSCREEN S.A. (BE) | 2011-08-04 | — | — | WO | disclosed |