Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MME | P08473 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.49 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.48 |
| ▸ | GSR | P00390 | 1/20 | 0.47 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.47 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.47 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2316276 | 1.00 | MEN1 (0.57) | MEN1KMT2AMMELMNAFFAR2 | |
| SCHEMBL2315478 | 0.90 | MEN1 (0.70) | MEN1KMT2AMMELMNAFFAR2 | |
| SCHEMBL2315472 | 0.90 | MEN1 (0.70) | MEN1KMT2AMMELMNAFFAR2 | |
| SCHEMBL2312027 | 0.85 | MEN1 (0.57) | MEN1KMT2AMMELMNAFFAR2 | |
| SCHEMBL2317674 | 0.85 | FFAR2 (0.69) | MEN1KMT2AMMELMNAFFAR2 | |
| SCHEMBL2317669 | 0.85 | FFAR2 (0.69) | MEN1KMT2AMMELMNAFFAR2 | |
| SCHEMBL2312033 | 0.85 | MEN1 (0.57) | MEN1KMT2AMMELMNAFFAR2 | |
| SCHEMBL2320196 | 0.85 | FFAR2 (0.69) | MEN1KMT2AMMELMNAFFAR2 | |
| SCHEMBL2319127 | 0.84 | MEN1 (0.54) | MEN1KMT2AMMELMNAFFAR2 | |
| SCHEMBL2319138 | 0.84 | MEN1 (0.54) | MEN1KMT2AMMELMNAFFAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092284-A1 | NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS | EUROSCREEN S.A. (BE) | 2011-08-04 | — | — | WO | claimed |