Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8320568 | 0.84 | ALDH1A1 (0.50) | HCAR2ALDH1A1LMNATDP1MAPK1 | |
| SCHEMBL24896641 | 0.80 | ALDH1A1 (0.46) | HCAR2ALDH1A1LMNATDP1MAPK1 | |
| SCHEMBL1070423 | 0.80 | HCAR2 (0.71) | HCAR2ALDH1A1LMNATDP1MAPK1 | |
| SCHEMBL1070426 | 0.80 | HCAR2 (0.71) | HCAR2ALDH1A1LMNATDP1MAPK1 | |
| SCHEMBL12181495 | 0.79 | ALDH1A1 (0.44) | HCAR2ALDH1A1LMNATDP1MAPK1 | |
| SCHEMBL14618833 | 0.79 | ALDH1A1 (0.44) | HCAR2ALDH1A1LMNATDP1MAPK1 | |
| SCHEMBL23222960 | 0.78 | ALDH1A1 (0.49) | HCAR2ALDH1A1LMNATDP1MAPK1 | |
| SCHEMBL26999202 | 0.77 | ALDH1A1 (0.55) | HCAR2ALDH1A1LMNATDP1MAPK1 | |
| SCHEMBL219575 | 0.75 | HCAR2 (0.65) | HCAR2ALDH1A1LMNATDP1MAPK1 | |
| SCHEMBL26330446 | 0.75 | HCAR2 (0.59) | HCAR2ALDH1A1LMNATDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3004053-B1 | A PROCESS FOR PREPARATION OF PYRROLES HAVING HYPOLIPIDEMIC HYPOCHOLESTEREMIC ACTIVITIES | CADILA HEALTHCARE LTD (IN) | 2021-03-24 | — | — | EP | disclosed |