Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SDCBP | O00560 | 5/20 | 0.39 |
| ▸ | SDC2 | P34741 | 5/20 | 0.39 |
| ▸ | THRB | P10828 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25467046 | 0.87 | LMNA (0.46) | LMNASDCBPSDC2THRBMEN1 | |
| SCHEMBL27318763 | 0.87 | LMNA (0.46) | LMNASDCBPSDC2THRBMEN1 | |
| SCHEMBL23729223 | 0.86 | LMNA (0.44) | LMNASDCBPSDC2THRBMEN1 | |
| SCHEMBL25742155 | 0.84 | LMNA (0.42) | LMNASDCBPSDC2THRBMEN1 | |
| SCHEMBL24078844 | 0.82 | SLC6A2 (0.42) | LMNATHRBMEN1KMT2AALOX15 | |
| SCHEMBL23986739 | 0.82 | LMNA (0.41) | LMNASDCBPSDC2THRBMEN1 | |
| SCHEMBL25571510 | 0.81 | LMNA (0.40) | LMNASDCBPSDC2THRBMEN1 | |
| SCHEMBL23128852 | 0.80 | ALDH1A1 (0.37) | MEN1KMT2AKDM4EGAA | |
| SCHEMBL25987058 | 0.79 | LMNA (0.43) | LMNATHRBMAPTGAA | |
| SCHEMBL27334328 | 0.78 | LMNA (0.35) | LMNASDCBPSDC2THRBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3795570-A1 | SUBSTITUTED QUINOLINE-8-CARBONITRILE DERIVATIVES HAVING ANDROGEN RECEPTOR DEGRADATION ACTIVITY AND USES THEREOF | Accutar Biotechnology Inc. (US) | 2021-03-24 | — | — | EP | disclosed |