Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 4/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | TSPO | P30536 | 1/20 | 0.32 |
| ▸ | TRIM58 | Q8NG06 | 1/20 | 0.32 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.32 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23129231 | 1.00 | TNKS2 (0.36) | TNKS2ACHEESR1ESR2BRD4 | |
| SCHEMBL18893005 | 0.92 | ACHE (0.41) | ACHEESR1 | |
| SCHEMBL18893075 | 0.92 | ACHE (0.41) | ACHEESR1 | |
| SCHEMBL23129228 | 0.91 | FEN1 (0.35) | TNKS2ACHEESR1ESR2BRD4 | |
| SCHEMBL19002146 | 0.90 | ACHE (0.36) | TNKS2ACHEESR1NR4A2PLA2G2A | |
| SCHEMBL18893041 | 0.90 | ACHE (0.42) | ACHEESR1ESR2 | |
| SCHEMBL23129227 | 0.89 | ACHE (0.35) | TNKS2ACHEESR1ESR2BRD4 | |
| SCHEMBL22019275 | 0.88 | ESR1 (0.36) | ACHEESR1 | |
| SCHEMBL22019686 | 0.87 | CYP1A2 (0.35) | TNKS2ACHEESR1ESR2BRD4 | |
| SCHEMBL15479331 | 0.87 | LMNA (0.39) | TNKS2ACHEESR1ESR2PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3406617-B1 | USE OF PHOSPHINE OXIDE COMPOUNDS IN A SEMICONDUCTING LAYER COMPRISED IN AN ELECTRONIC DEVICE | NOVALED GMBH (DE) | 2021-03-24 | — | — | EP | disclosed |