SCHEMBL2312952

SCHEMBL2312952

O=C(O)CC(Cc1ccc(Cl)cc1)NC(=O)Cc1ccc(Cl)c(Cl)c1

nearest known ligand 0.62

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MME P08473 11/20 0.62
FFAR2 O15552 1/20 0.60
MMEL1 Q495T6 5/20 0.60
KMT2A Q03164 3/20 0.48
MEN1 O00255 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
PSMB8 P28062 1/20 0.47
PSMB5 P28074 1/20 0.47
CNR2 P34972 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2312944 1.00 MME (0.62) MMEFFAR2MMEL1KMT2AMEN1
SCHEMBL2315872 0.95 MME (0.58) MMEFFAR2MMEL1KMT2AMEN1
SCHEMBL2315867 0.95 MME (0.58) MMEFFAR2MMEL1KMT2AMEN1
SCHEMBL2320594 0.93 FFAR2 (0.58) MMEFFAR2MMEL1KMT2AMEN1
SCHEMBL2320587 0.93 FFAR2 (0.58) MMEFFAR2MMEL1KMT2AMEN1
SCHEMBL2316114 0.90 FFAR2 (0.55) MMEFFAR2MMEL1PSMB8PSMB5
SCHEMBL2316107 0.90 FFAR2 (0.55) MMEFFAR2MMEL1PSMB8PSMB5
SCHEMBL2314965 0.89 MME (0.71) MMEFFAR2MMEL1KMT2APSMB8
SCHEMBL2314959 0.89 MME (0.71) MMEFFAR2MMEL1KMT2APSMB8
SCHEMBL2320620 0.88 FFAR2 (0.71) MMEFFAR2MMEL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011092284-A1 NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS EUROSCREEN S.A. (BE) 2011-08-04 WO claimed