Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1669840 | 0.98 | LMNA (0.59) | LMNASLC1A3SLC1A2SLC1A1ALOX5 | |
| SCHEMBL1672623 | 0.95 | LMNA (0.55) | LMNASLC1A3SLC1A2SLC1A1ALOX5 | |
| SCHEMBL25381860 | 0.90 | LMNA (0.50) | LMNASLC1A3SLC1A2SLC1A1ALOX5 | |
| SCHEMBL1444506 | 0.90 | LMNA (0.43) | LMNASLC1A3SLC1A2SLC1A1ALOX5 | |
| SCHEMBL12987175 | 0.87 | LMNA (0.50) | LMNASLC1A3SLC1A2SLC1A1ALOX5 | |
| SCHEMBL696997 | 0.87 | LMNA (0.50) | LMNASLC1A3SLC1A2SLC1A1ALOX5 | |
| SCHEMBL6895798 | 0.87 | LMNA (0.50) | LMNASLC1A3SLC1A2SLC1A1ALOX5 | |
| SCHEMBL3117465 | 0.87 | ALDH1A1 (0.52) | LMNASLC1A3SLC1A2SLC1A1KMT2A | |
| SCHEMBL6032436 | 0.86 | LMNA (0.53) | LMNASLC1A3SLC1A2SLC1A1ALOX5 | |
| SCHEMBL698390 | 0.85 | LMNA (0.52) | LMNASLC1A3SLC1A2SLC1A1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3154989-B1 | BETA-LACTAMASE INHIBITORS | VENATORX PHARMACEUTICALS INC (US) | 2021-03-24 | — | — | EP | disclosed |