Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17347818 | 1.00 | KMT2A (0.32) | KMT2AHTTUSP2TSHRALDH1A1 | |
| SCHEMBL17337334 | 0.92 | TSHR (0.37) | KMT2AUSP2TSHRALDH1A1KDM4E | |
| SCHEMBL17337192 | 0.92 | TSHR (0.37) | KMT2AUSP2TSHRALDH1A1KDM4E | |
| SCHEMBL17337133 | 0.90 | RAB9A (0.35) | KMT2AHTTALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL17337541 | 0.90 | RAB9A (0.35) | KMT2AHTTALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL19228054 | 0.89 | KDM4E (0.31) | TSHRKDM4E | |
| SCHEMBL23129992 | 0.89 | TSHR (0.38) | TSHRALDH1A1TRPA1KDM4ESMN1; SMN2 | |
| SCHEMBL17337419 | 0.89 | TSHR (0.38) | TSHRALDH1A1TRPA1KDM4ESMN1; SMN2 | |
| SCHEMBL23129931 | 0.88 | PRKCB (0.32) | — | |
| SCHEMBL17337239 | 0.88 | PRKCB (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3154989-B1 | BETA-LACTAMASE INHIBITORS | VENATORX PHARMACEUTICALS INC (US) | 2021-03-24 | — | — | EP | disclosed |