Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 9/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19562917 | 0.88 | SLC22A12 (0.51) | SLC22A12P2RX7MAPKAPK2HSD11B1MET | |
| SCHEMBL17899837 | 0.82 | SLC22A12 (0.54) | SLC22A12P2RX7 | |
| SCHEMBL17899839 | 0.82 | SLC22A12 (0.70) | SLC22A12 | |
| SCHEMBL23129259 | 0.76 | SLC22A12 (0.38) | SLC22A12P2RX7MAPKAPK2HSD11B1SYK | |
| SCHEMBL28388332 | 0.74 | SLC22A12 (0.46) | SLC22A12P2RX7MAPKAPK2HSD11B1SYK | |
| SCHEMBL28387584 | 0.72 | ELANE (0.40) | SLC22A12P2RX7SYKKDM4EMAPT | |
| SCHEMBL19435524 | 0.72 | IL1B (0.45) | MAPKAPK2HSD11B1MAP4K4TDO2KDM4E | |
| SCHEMBL19435494 | 0.72 | GAK (0.44) | MAPKAPK2HSD11B1SYKMAP4K4KDM4E | |
| SCHEMBL19435459 | 0.70 | ELANE (0.41) | SLC22A12P2RX7 | |
| SCHEMBL17899867 | 0.69 | SLC22A12 (0.46) | SLC22A12P2RX7HSD11B1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3241822-B1 | URAT1 INHIBITOR | NIPPON CHEMIPHAR CO (JP) | 2021-03-24 | — | — | EP | disclosed |