Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.34 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17347688 | 1.00 | MTNR1A (0.34) | MTNR1AMTNR1BHTR4CA12CA1 | |
| SCHEMBL23129896 | 0.93 | MTNR1A (0.32) | MTNR1AMTNR1B | |
| SCHEMBL17347830 | 0.93 | MTNR1A (0.32) | MTNR1AMTNR1B | |
| SCHEMBL23129972 | 0.90 | MTNR1A (0.33) | MTNR1AMTNR1BCA12CA1CA2 | |
| SCHEMBL17347750 | 0.90 | MTNR1A (0.33) | MTNR1AMTNR1BCA12CA1CA2 | |
| SCHEMBL23129888 | 0.89 | MTNR1A (0.32) | MTNR1AMTNR1BHTR4CA12CA1 | |
| SCHEMBL17347788 | 0.89 | MTNR1A (0.32) | MTNR1AMTNR1BHTR4CA12CA1 | |
| SCHEMBL17347742 | 0.89 | CAT (0.31) | HTR4 | |
| SCHEMBL23129920 | 0.89 | CAT (0.31) | HTR4 | |
| SCHEMBL18662420 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3154989-B1 | BETA-LACTAMASE INHIBITORS | VENATORX PHARMACEUTICALS INC (US) | 2021-03-24 | — | — | EP | disclosed |