Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.30 |
| ▸ | CAT | P04040 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17347830 | 1.00 | MTNR1A (0.32) | MTNR1AMTNR1BCYP1A2MAPTCYP2C9 | |
| SCHEMBL23129893 | 0.93 | MTNR1A (0.34) | MTNR1AMTNR1B | |
| SCHEMBL17347688 | 0.93 | MTNR1A (0.34) | MTNR1AMTNR1B | |
| SCHEMBL17347742 | 0.91 | CAT (0.31) | CAT | |
| SCHEMBL23129920 | 0.91 | CAT (0.31) | CAT | |
| SCHEMBL18662420 | 0.90 | — | — | |
| SCHEMBL18662422 | 0.90 | — | — | |
| SCHEMBL23129902 | 0.90 | PRKCB (0.33) | MTNR1AMTNR1B | |
| SCHEMBL17347825 | 0.90 | PRKCB (0.33) | MTNR1AMTNR1B | |
| SCHEMBL19663665 | 0.90 | MTNR1A (0.31) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3154989-B1 | BETA-LACTAMASE INHIBITORS | VENATORX PHARMACEUTICALS INC (US) | 2021-03-24 | — | — | EP | disclosed |