Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23130173 | 0.92 | MTNR1A (0.36) | MTNR1AMTNR1B | |
| SCHEMBL17337356 | 0.91 | MTNR1A (0.37) | MTNR1AMTNR1BCYP1A2ALOX15MAPT | |
| SCHEMBL17337359 | 0.91 | MTNR1A (0.37) | MTNR1AMTNR1BCYP1A2ALOX15MAPT | |
| SCHEMBL22514014 | 0.90 | MTNR1A (0.38) | MTNR1AMTNR1BCYP1A2ALOX15MAPT | |
| SCHEMBL23130045 | 0.90 | — | — | |
| SCHEMBL17337345 | 0.89 | KMT2A (0.36) | MTNR1AMTNR1BCYP1A2ALOX15MAPT | |
| SCHEMBL17337346 | 0.89 | KMT2A (0.36) | MTNR1AMTNR1BCYP1A2ALOX15MAPT | |
| SCHEMBL17337157 | 0.89 | PRKCB (0.34) | MTNR1AMTNR1BCYP1A2ALOX15MAPT | |
| SCHEMBL18957334 | 0.89 | TDP1 (0.36) | MTNR1AMTNR1BCYP1A2ALOX15MAPT | |
| SCHEMBL17337154 | 0.89 | PRKCB (0.34) | MTNR1AMTNR1BCYP1A2ALOX15MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3154989-B1 | BETA-LACTAMASE INHIBITORS | VENATORX PHARMACEUTICALS INC (US) | 2021-03-24 | — | — | EP | disclosed |