Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 6/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.38 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17347756 | 1.00 | MTNR1B (0.38) | MTNR1BMTNR1AKCNA3L3MBTL1PDE4A | |
| SCHEMBL17347815 | 0.93 | MTNR1A (0.36) | MTNR1BMTNR1AKCNA3L3MBTL1 | |
| SCHEMBL23130020 | 0.93 | MTNR1A (0.36) | MTNR1BMTNR1AKCNA3L3MBTL1 | |
| SCHEMBL23837457 | 0.90 | MTNR1B (0.36) | MTNR1BMTNR1AKCNA3 | |
| SCHEMBL23129972 | 0.89 | MTNR1A (0.33) | MTNR1BMTNR1A | |
| SCHEMBL17347750 | 0.89 | MTNR1A (0.33) | MTNR1BMTNR1A | |
| SCHEMBL17347775 | 0.89 | MTNR1A (0.33) | MTNR1BMTNR1AL3MBTL1 | |
| SCHEMBL23129720 | 0.89 | MTNR1A (0.33) | MTNR1BMTNR1AL3MBTL1 | |
| SCHEMBL23129888 | 0.89 | MTNR1A (0.32) | MTNR1BMTNR1A | |
| SCHEMBL17347788 | 0.89 | MTNR1A (0.32) | MTNR1BMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3154989-B1 | BETA-LACTAMASE INHIBITORS | VENATORX PHARMACEUTICALS INC (US) | 2021-03-24 | — | — | EP | disclosed |