Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17347794 | 1.00 | MAPT (0.35) | MAPTLMNAMAPK1CASP1CASP7 | |
| SCHEMBL23837314 | 0.92 | GAA (0.30) | MAPTLMNAMAPK1CASP1CASP7 | |
| SCHEMBL17347678 | 0.92 | ALDH1A1 (0.34) | MAPTLMNAALDH1A1KDM4EHPGD | |
| SCHEMBL23129979 | 0.92 | ALDH1A1 (0.34) | MAPTLMNAALDH1A1KDM4EHPGD | |
| SCHEMBL17347813 | 0.89 | NPSR1 (0.35) | MAPTLMNAMAPK1ALDH1A1KDM4E | |
| SCHEMBL23130170 | 0.88 | — | — | |
| SCHEMBL17347829 | 0.88 | — | — | |
| SCHEMBL23129975 | 0.88 | MTNR1A (0.31) | ALDH1A1KDM4EPOLBKMT2A | |
| SCHEMBL17347660 | 0.88 | MTNR1A (0.31) | ALDH1A1KDM4EPOLBKMT2A | |
| SCHEMBL23837577 | 0.88 | MAPT (0.33) | MAPTLMNAMAPK1CASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3154989-B1 | BETA-LACTAMASE INHIBITORS | VENATORX PHARMACEUTICALS INC (US) | 2021-03-24 | — | — | EP | disclosed |