SCHEMBL2313102

SCHEMBL2313102

O=C(O)CCCNC=C1N=C(c2ccccc2)OC1=O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSNK2A2 P19784 3/20 0.49
CSNK2B P67870 3/20 0.49
CSNK2A1 P68400 3/20 0.49
SMN1; SMN2 Q16637 2/20 0.47
F2 P00734 1/20 0.45
F10 P00742 1/20 0.45
PLG P00747 1/20 0.45
PLAU P00749 1/20 0.45
PLAT P00750 1/20 0.45
KLKB1 P03952 1/20 0.45
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
DAPK3 O43293 1/20 0.42
PLCG2 P16885 1/20 0.41
KMT2A Q03164 4/20 0.41
MAPT P10636 3/20 0.41
ALDH1A1 P00352 2/20 0.41
LMNA P02545 1/20 0.41
RECQL P46063 1/20 0.41
TDP1 Q9NUW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2313095 1.00 CSNK2A2 (0.49) CSNK2A2CSNK2BCSNK2A1SMN1; SMN2F2
SCHEMBL5516539 0.84 SMN1; SMN2 (0.51) CSNK2A2CSNK2BCSNK2A1SMN1; SMN2F2
SCHEMBL5516544 0.84 SMN1; SMN2 (0.51) CSNK2A2CSNK2BCSNK2A1SMN1; SMN2F2
SCHEMBL4804024 0.71 SMN1; SMN2 (0.63) CSNK2A2CSNK2BCSNK2A1SMN1; SMN2F2
SCHEMBL12450700 0.71 SMN1; SMN2 (0.63) CSNK2A2CSNK2BCSNK2A1SMN1; SMN2F2
SCHEMBL4804018 0.71 SMN1; SMN2 (0.63) CSNK2A2CSNK2BCSNK2A1SMN1; SMN2F2
SCHEMBL10595200 0.69 MEN1 (0.51) SMN1; SMN2F2NPC1RAB9ADAPK3
SCHEMBL10595203 0.69 MEN1 (0.51) SMN1; SMN2F2NPC1RAB9ADAPK3
Gamma-Aminobutyric Acid SCHEMBL2897912 0.68 KMT2A (0.41) CSNK2A2CSNK2BCSNK2A1SMN1; SMN2F2
SCHEMBL24524106 0.68 SMN1; SMN2 (0.63) CSNK2A2CSNK2BCSNK2A1SMN1; SMN2F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210254056-A1 IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS CAMP4 THERAPEUTICS CORPORATION 2021-08-19 US disclosed
US-9873871-B2 Method of obtaining antibodies of interest and nucleotides encoding same SINGLE CELL TECHNOLOGY, INC. (US) 2018-01-23 US disclosed
US-20160201054-A1 METHOD OF OBTAINING ANTIBODIES OF INTEREST AND NUCLEOTIDES ENCODING SAME SINGLE CELL TECHNOLOGY, INC. 2016-07-14 US disclosed
US-9328172-B2 Method of obtaining antibodies of interest and nucleotides encoding same SINGLE CELL TECHNOLOGY, INC. (US) 2016-05-03 US disclosed
US-8309317-B2 Method of screening single cells for the production of biologically active agents SINGLE CELL TECHNOLOGY, INC. (US) 2012-11-13 US disclosed
US-20110190148-A1 METHOD OF OBTAINING ANTIBODIES OF INTEREST AND NUCLEOTIDES ENCODING SAME SINGLE CELL TECHNOLOGY, INC. 2011-08-04 US disclosed
US-20100035763-A1 METHOD OF SCREENING SINGLE CELLS FOR THE PRODUCTION OF BIOLOGICALLY ACTIVE AGENTS SINGLE CELL TECHNOLOGY, INC. 2010-02-11 US disclosed