Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.41 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aminocaproic Acid SCHEMBL379308 | 0.95 | ALDH1A1 (0.44) | KMT2ALMNATHRBBLMNPSR1 | |
| SCHEMBL2714415 | 0.81 | SMN1; SMN2 (0.50) | KMT2ALMNANPSR1CYP1A2ALDH1A1 | |
| SCHEMBL24534659 | 0.77 | SMN1; SMN2 (0.47) | KMT2ALMNANPSR1ALDH1A1CSNK2A2 | |
| Gamma-Aminobutyric Acid SCHEMBL5795191 | 0.76 | HDAC3 (0.41) | KMT2ALMNATHRBBLMNPSR1 | |
| Phthalic Anhydride SCHEMBL10455461 | 0.71 | HDAC3 (0.54) | KMT2ALMNATHRBBLMNPSR1 | |
| Gamma-Aminobutyric Acid SCHEMBL28119738 | 0.69 | HDAC3 (0.60) | KMT2ALMNATHRBBLMNPSR1 | |
| SCHEMBL2313102 | 0.68 | CSNK2A2 (0.49) | KMT2ALMNAALDH1A1CSNK2A2CSNK2B | |
| SCHEMBL2313095 | 0.68 | CSNK2A2 (0.49) | KMT2ALMNAALDH1A1CSNK2A2CSNK2B | |
| SCHEMBL24534516 | 0.68 | GSTP1 (0.46) | KMT2ATSHRALDH1A1CSNK2A2CSNK2B | |
| Gamma-Aminobutyric Acid SCHEMBL27860343 | 0.68 | LMNA (0.88) | KMT2ALMNATHRBBLMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2224006-A1 | Production of anti-self antibodies from antibody segment repertoires and displayed on phage | MedImmune Limited (GB) | 2010-09-01 | — | — | EP | disclosed |
| EP-1696031-B1 | Production of anti-self antibodies from antibody segment repertoires and displayed on phage | MEDIMMUNE LTD (GB) | 2010-04-07 | — | — | EP | disclosed |
| US-20090325815-A1 | PRODUCTION OF ANTI-SELF ANTIBODIES FROM ANTIBODY SEGMENT REPERTOIRES AND DISPLAYED ON PHAGE | MEDICAL RESEARCH COUNCIL (GB) | 2009-12-31 | — | — | US | disclosed |
| EP-1024191-B1 | Production of anti-self antibodies from antibody segment repertoires and displayed on phage | MEDICAL RES COUNCIL (GB) | 2008-09-10 | — | — | EP | disclosed |
| US-20080050359-A1 | PRODUCTION OF ANTI-SELF ANTIBODIES FROM ANTIBODY SEGMENT REPERTOIRES AND DISPLAYED ON PHAGE | MEDICAL RESEARCH COUNCIL (GB) | 2008-02-28 | — | — | US | disclosed |
| US-20070232790-A1 | PRODUCTION OF ANTI-SELF ANTIBODIES FROM ANTIBODY SEGMENT REPERTOIRES AND DISPLAYED ON PHAGE | MEDICAL RESEARCH COUNCIL (GB) | 2007-10-04 | — | — | US | disclosed |
| US-7195866-B2 | Production of anti-self antibodies from antibody segment repertoires and displayed on phage | MEDICAL RESEARCH COUNCIL (GB) | 2007-03-27 | — | — | US | disclosed |
| EP-1696031-A1 | Production of anti-self antibodies from antibody segment repertoires and displayed on phage | Cambridge Antibody Technology Limited (GB) | 2006-08-30 | — | — | EP | disclosed |
| EP-0616640-B1 | PRODUCTION OF ANTI-SELF ANTIBODIES FROM ANTIBODY SEGMENT REPERTOIRES AND DISPLAYED ON PHAGE | MEDICAL RES COUNCIL (GB) | 2004-09-01 | — | — | EP | disclosed |
| US-20030190674-A1 | Production of anti-self antibodies from antibody segment repertoires and displayed on phage | MEDICAL RESEARCH COUNCIL | 2003-10-09 | — | — | US | disclosed |
| US-6555313-B1 | Antibodies directed against self antigens isolated using bacteriophage display technology | MEDICAL RESEARCH COUNCIL (GB) | 2003-04-29 | — | — | US | disclosed |
| US-6544731-B1 | Genetic engineering; binding antibodies | MEDICAL RESEARCH COUNCIL (GB) | 2003-04-08 | — | — | US | disclosed |
| US-6521404-B1 | Gene expression of library bacteriophage particles with very light domain antibodies and synthetic very heavy antibodies displayed on surface | MEDICAL RESEARCH COUNCIL (GB) | 2003-02-18 | — | — | US | disclosed |
| EP-1024191-A2 | Production of chimeric antibodies from antibody segment repertoires and displayed on phage | MEDICAL RESEARCH COUNCIL (GB) | 2000-08-02 | — | — | EP | disclosed |
| EP-0605522-B1 | Methods for the production of humanized antibodies | MEDICAL RES COUNCIL (GB) | 1999-06-23 | — | — | EP | disclosed |
| US-5885793-A | Production of anti-self antibodies from antibody segment repertoires and displayed on phage | MEDICAL RESEARCH COUNCIL (GB) | 1999-03-23 | — | — | US | disclosed |
| EP-0616640-A1 | PRODUCTION OF ANTI-SELF ANTIBODIES FROM ANTIBODY SEGMENT REPERTOIRES AND DISPLAYED ON PHAGE | MEDICAL RESEARCH COUNCIL (GB) | 1994-09-28 | — | — | EP | disclosed |
| EP-0605522-A1 | PRODUCTION OF CHIMERIC ANTIBODIES - A COMBINATORIAL APPROACH | MEDICAL RESEARCH COUNCIL (GB) | 1994-07-13 | — | — | EP | disclosed |
| WO-1993011236-A1 | PRODUCTION OF ANTI-SELF ANTIBODIES FROM ANTIBODY SEGMENT REPERTOIRES AND DISPLAYED ON PHAGE | MEDICAL RESEARCH COUNCIL (GB) | 1993-06-10 | — | — | WO | disclosed |
| WO-1993006213-A1 | PRODUCTION OF CHIMERIC ANTIBODIES - A COMBINATORIAL APPROACH | MEDICAL RESEARCH COUNCIL (GB) | 1993-04-01 | — | — | WO | disclosed |