Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 5/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 5/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SPR | P35270 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23134742 | 0.90 | DDB1 (0.44) | DDB1CRBNEGFRALDH1A1TSHR | |
| SCHEMBL28783614 | 0.88 | DDB1 (0.47) | DDB1CRBNEGFRALDH1A1TSHR | |
| SCHEMBL23121669 | 0.87 | DDB1 (0.46) | DDB1CRBNEGFRALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL23122759 | 0.86 | DDB1 (0.46) | DDB1CRBNEGFRALDH1A1TSHR | |
| SCHEMBL30009143 | 0.85 | CRBN (0.49) | DDB1CRBN | |
| SCHEMBL23123218 | 0.85 | CRBN (0.49) | DDB1CRBN | |
| SCHEMBL27148853 | 0.83 | CRBN (0.46) | DDB1CRBN | |
| SCHEMBL23121717 | 0.79 | DDB1 (0.40) | DDB1CRBNEGFRALDH1A1TSHR | |
| SCHEMBL23123241 | 0.79 | DDB1 (0.40) | DDB1CRBNEGFRALDH1A1TSHR | |
| SCHEMBL23134720 | 0.79 | DDB1 (0.44) | DDB1CRBNALDH1A1TSHRMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021055295-A1 | BRD9 BIFUNCTIONAL DEGRADERS AND THEIR METHODS OF USE | NOVARTIS AG (CH) | 2021-03-25 | — | — | WO | disclosed |