Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 3/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23134050 | 0.88 | CRBN (0.42) | DDB1CRBNALDH1A1TSHR | |
| SCHEMBL23133980 | 0.88 | DDB1 (0.38) | DDB1CRBNALDH1A1TSHRHCRTR1 | |
| SCHEMBL28783614 | 0.88 | DDB1 (0.47) | DDB1CRBNALDH1A1TSHRHCRTR1 | |
| SCHEMBL23121717 | 0.86 | DDB1 (0.40) | DDB1CRBNALDH1A1TSHRHCRTR1 | |
| Hydrochloric Acid SCHEMBL23121758 | 0.85 | DDB1 (0.40) | DDB1CRBNALDH1A1TSHRHCRTR1 | |
| SCHEMBL23123147 | 0.84 | HSD11B1 (0.37) | DDB1CRBNTSHRHPGDMGLL | |
| SCHEMBL23122908 | 0.84 | CXCR3 (0.48) | DDB1CRBNKMT2A | |
| SCHEMBL23122387 | 0.83 | NR3C1 (0.38) | CRBNALDH1A1HSD11B1MEN1KMT2A | |
| SCHEMBL23121669 | 0.81 | DDB1 (0.46) | DDB1CRBNALDH1A1TSHRHCRTR1 | |
| Hydrochloric Acid SCHEMBL23122759 | 0.81 | DDB1 (0.46) | DDB1CRBNALDH1A1TSHRHCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114641473-A | BRD9 bifunctional degradation agent and use method thereof | 诺华股份有限公司 | 2022-06-17 | — | — | CN | disclosed |
| WO-2021055295-A1 | BRD9 BIFUNCTIONAL DEGRADERS AND THEIR METHODS OF USE | NOVARTIS AG (CH) | 2021-03-25 | — | — | WO | disclosed |