SCHEMBL27148853

SCHEMBL27148853

CC(C)(C)OC(=O)N1CC(OC2CCN(C(=O)c3cccc(N4CCC(=O)NC4=O)c3)CC2)C1

nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 6/20 0.46
▸ DDB1 Q16531 5/20 0.46
▸ USP30 Q70CQ3 2/20 0.41
▸ GPR119 Q8TDV5 7/20 0.40
▸ EPHX2 P34913 1/20 0.40
▸ KDM1A O60341 1/20 0.39
▸ KDM4E B2RXH2 1/20 0.38
▸ PKM P14618 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30009143 0.95 CRBN (0.49) CRBNDDB1USP30GPR119EPHX2
SCHEMBL23123218 0.95 CRBN (0.49) CRBNDDB1USP30GPR119EPHX2
SCHEMBL23134050 0.88 CRBN (0.42) CRBNDDB1USP30GPR119EPHX2
SCHEMBL23173797 0.87 CRBN (0.56) CRBNDDB1USP30GPR119EPHX2
SCHEMBL28783614 0.84 DDB1 (0.47) CRBNDDB1KDM4E
SCHEMBL30392744 0.83 CRBN (0.51) CRBNDDB1USP30EPHX2
SCHEMBL23121669 0.83 DDB1 (0.46) CRBNDDB1
SCHEMBL23134742 0.83 DDB1 (0.44) CRBNDDB1
SCHEMBL23133973 0.83 DDB1 (0.44) CRBNDDB1
Hydrochloric Acid SCHEMBL23122759 0.82 DDB1 (0.46) CRBNDDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4548937-A1 ANTIBODY-DRUG COMPLEX Eisai R&D Management Co., Ltd. (JP) 2025-05-07 — — EP disclosed
US-20240148895-A1 ANTIBODY-DRUG CONJUGATE EISAI R&D MANAGEMENT CO., LTD. (JP) 2024-05-09 — — US disclosed
WO-2024043319-A1 ANTIBODY-DRUG COMPLEX エーザイ・アール・アンド・ディー・マネジメント株式会社 2024-02-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240148895-A1 ANTIBODY-DRUG CONJUGATE ANTXR2, FCGR1A, HAX1 CRBN 1543/4885DDB1 200/4885USP30 2650/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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