Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | MIF | P14174 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14263144 | 0.82 | TAAR1 (0.50) | TAAR1MIFPPARDPPARAMAOB | |
| SCHEMBL28859175 | 0.80 | PPARA (0.42) | TAAR1MIFPPARDPPARAMAOB | |
| SCHEMBL23134271 | 0.79 | MEN1 (0.44) | TAAR1PPARDPPARAMAOBIDO1 | |
| SCHEMBL28956156 | 0.79 | PPARA (0.52) | PPARDPPARAHRH3 | |
| SCHEMBL14263243 | 0.78 | MAOB (0.53) | TAAR1MAOBIDO1MEN1KMT2A | |
| SCHEMBL27830060 | 0.77 | TAAR1 (0.52) | TAAR1MIFPPARDPPARAMAOB | |
| SCHEMBL14274242 | 0.76 | TAAR1 (0.55) | TAAR1MIFPPARDPPARAMAOB | |
| SCHEMBL6003117 | 0.75 | PTGES (0.46) | TAAR1PPARDPPARAMAOBIDO1 | |
| SCHEMBL1696674 | 0.73 | TAAR1 (0.61) | TAAR1MIFMAOBIDO1KCNH2 | |
| SCHEMBL934227 | 0.72 | TAAR1 (0.73) | TAAR1MIFMAOBIDO1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210087184-A1 | AMINO-BENZOISOTHIAZOLE AND AMINO-BENZOISOTHIADIAZOLE AMIDE COMPOUNDS | ALCON INC. (CH) | 2021-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210087184-A1 | AMINO-BENZOISOTHIAZOLE AND AMINO-BENZOISOTHIADIAZOLE AMIDE COMPOUNDS | ATM, MAP3K15, MAP3K3 | TAAR1 2233/4885MIF 1153/4885PPARD 293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.