Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 3/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.46 |
| ▸ | PPARG | P37231 | 3/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6003120 | 0.84 | EPHX1 (0.47) | PTGESALOX5PPARGTAAR1KCNH2 | |
| SCHEMBL8780020 | 0.80 | PPARG (0.46) | PTGESALOX5PPARGPSEN1 | |
| SCHEMBL23134271 | 0.78 | MEN1 (0.44) | PTGESALOX5PPARGTAAR1MEN1 | |
| SCHEMBL23134263 | 0.75 | TAAR1 (0.47) | TAAR1MEN1KMT2AKCNH2TMEM97 | |
| SCHEMBL14263144 | 0.75 | TAAR1 (0.50) | TAAR1MEN1KMT2AFDFT1KCNH2 | |
| SCHEMBL3910376 | 0.74 | TAAR1 (0.57) | TAAR1FDFT1MAOBIDO1 | |
| SCHEMBL27652962 | 0.73 | CTSK (0.47) | PTGESALOX5PPARGKCNH2IDO1 | |
| SCHEMBL2089930 | 0.72 | TAAR1 (0.55) | TAAR1MAOB | |
| SCHEMBL2615716 | 0.71 | FAAH (0.57) | TAAR1 | |
| SCHEMBL9352104 | 0.71 | TAAR1 (0.53) | TAAR1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |