Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.58 |
| ▸ | MME | P08473 | 6/20 | 0.57 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 2/20 | 0.48 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.45 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.45 |
| ▸ | MMEL1 | Q495T6 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | CCR3 | P51677 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2313586 | 1.00 | PIN1 (0.58) | PIN1MMEFFAR2CNR1ERCC1 | |
| SCHEMBL2318052 | 0.89 | MME (0.53) | PIN1MMEFFAR2CNR1MMEL1 | |
| SCHEMBL2318057 | 0.89 | MME (0.53) | PIN1MMEFFAR2CNR1MMEL1 | |
| SCHEMBL2320587 | 0.87 | FFAR2 (0.58) | MMEFFAR2MMEL1LMNAFFAR1 | |
| SCHEMBL2320594 | 0.87 | FFAR2 (0.58) | MMEFFAR2MMEL1LMNAFFAR1 | |
| SCHEMBL2315599 | 0.86 | FFAR2 (0.71) | MMEFFAR2MMEL1 | |
| SCHEMBL2320620 | 0.86 | FFAR2 (0.71) | MMEFFAR2MMEL1 | |
| SCHEMBL2320630 | 0.86 | FFAR2 (0.71) | MMEFFAR2MMEL1 | |
| SCHEMBL2315608 | 0.86 | FFAR2 (0.71) | MMEFFAR2MMEL1 | |
| SCHEMBL2319372 | 0.84 | FFAR2 (0.57) | MMEFFAR2MMEL1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092284-A1 | NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS | EUROSCREEN S.A. (BE) | 2011-08-04 | — | — | WO | claimed |