Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2210266 | 0.85 | BRD4 (0.44) | BRD4EPHX2EPHX1 | |
| SCHEMBL12669611 | 0.84 | BRD4 (0.42) | BRD4EPHX2EPHX1 | |
| SCHEMBL11310192 | 0.82 | ALDH1A1 (0.47) | EPHX2EPHX1CYP1A2TDP1 | |
| SCHEMBL11094974 | 0.82 | SMN1; SMN2 (0.50) | MAPT | |
| SCHEMBL2864044 | 0.81 | BRD4 (0.50) | BRD4 | |
| SCHEMBL14146004 | 0.81 | GLS (0.39) | EPHX2EPHX1 | |
| SCHEMBL12946004 | 0.80 | BRD4 (0.38) | BRD4EPHX2EPHX1 | |
| SCHEMBL10086273 | 0.80 | AKR1C3 (0.46) | EPHX2EPHX1CYP1A2TDP1 | |
| SCHEMBL14086615 | 0.80 | TSHR (0.44) | EPHX2EPHX1 | |
| SCHEMBL13713534 | 0.80 | EPHX2 (0.47) | BRD4EPHX2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113272301-B | Heterocyclic compound, intermediate, preparation method and application thereof | 武汉朗来科技发展有限公司 | 2024-04-26 | — | — | CN | disclosed |
| WO-2021055376-A1 | IL-17A MODULATORS AND USES THEREOF | DICE ALPHA, INC. (US) | 2021-03-25 | — | — | WO | disclosed |