Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.66 |
| ▸ | CASP1 | P29466 | 1/20 | 0.66 |
| ▸ | MYH9 | P35579 | 1/20 | 0.66 |
| ▸ | MYH10 | P35580 | 1/20 | 0.66 |
| ▸ | CASP7 | P55210 | 1/20 | 0.66 |
| ▸ | HBB | P68871 | 1/20 | 0.66 |
| ▸ | MYH2 | Q9UKX2 | 1/20 | 0.65 |
| ▸ | METAP2 | P50579 | 11/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26214026 | 0.86 | MEN1 (0.68) | MEN1KMT2ACYP3A4MAPTCYP1A2 | |
| SCHEMBL18214930 | 0.86 | KMT2A (0.74) | MEN1KMT2ACYP3A4MAPTCYP1A2 | |
| SCHEMBL21067295 | 0.86 | KMT2A (0.74) | MEN1KMT2ACYP3A4MAPTCYP1A2 | |
| SCHEMBL23137832 | 0.82 | MEN1 (0.66) | MEN1KMT2ACYP3A4MAPTCYP1A2 | |
| SCHEMBL26214101 | 0.81 | MEN1 (0.65) | MEN1KMT2ACYP3A4MAPTCYP1A2 | |
| SCHEMBL23136659 | 0.81 | MEN1 (0.65) | MEN1KMT2ACYP3A4MAPTCYP1A2 | |
| SCHEMBL23000093 | 0.81 | MEN1 (0.65) | MEN1KMT2ACYP3A4MAPTCYP1A2 | |
| SCHEMBL23136655 | 0.81 | MEN1 (0.65) | MEN1KMT2ACYP3A4MAPTCYP1A2 | |
| SCHEMBL23909334 | 0.81 | MEN1 (0.70) | MEN1KMT2ACYP3A4MAPTCYP1A2 | |
| SCHEMBL23917036 | 0.81 | MEN1 (0.77) | MEN1KMT2ACYP3A4MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210087201-A1 | PHARMACEUTICALLY EFFECTIVE COMPOUNDS INHIBITING SELECTIVELY THE MYOSIN 2 ISOFORMS | EÖTVÖS LORÁND TUDOMÁNYEGYETEM (HU) | 2021-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210087201-A1 | PHARMACEUTICALLY EFFECTIVE COMPOUNDS INHIBITING SELECTIVELY THE MYOSIN 2 ISOFORMS | MYH2, MYLK2, MYO1B | MEN1 2122/4885KMT2A 3113/4885CYP3A4 1590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.