Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 2/20 | 0.56 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.56 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.56 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.55 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.55 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.54 |
| ▸ | SCD | O00767 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | LCK | P06239 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.49 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23136931 | 0.87 | CASP3 (0.52) | CASP3SENP8SENP7SENP6DYRK1A | |
| SCHEMBL23135805 | 0.81 | CSNK1D (0.63) | DYRK1ASCDMEN1KMT2AMAPT | |
| SCHEMBL23135818 | 0.81 | DYRK1A (0.68) | CASP3SENP8SENP7SENP6DYRK1A | |
| SCHEMBL23136892 | 0.78 | CASP3 (0.73) | CASP3SENP8SENP7SENP6DYRK1A | |
| SCHEMBL17667168 | 0.78 | NPC1 (0.70) | CASP3SENP8SENP7SENP6DYRK1A | |
| SCHEMBL23136889 | 0.76 | MAPT (0.75) | CASP3SENP8SENP7SENP6DYRK1A | |
| SCHEMBL28226353 | 0.76 | DYRK1A (0.52) | CASP3SENP8SENP7SENP6DYRK1A | |
| SCHEMBL29788 | 0.75 | HSD17B1 (0.82) | DYRK1ADYRK1BLRRK2SCDSMN1; SMN2 | |
| SCHEMBL23135813 | 0.73 | DYRK1A (0.60) | DYRK1ADYRK1BSCDRAB9AMAPT | |
| SCHEMBL17251803 | 0.73 | CASP3 (0.65) | CASP3SENP8SENP7SENP6DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210087290-A1 | COMPOUNDS WHICH SPECIFICALLY BIND TO CD38 FOR USE IN THE TREATMENT OF NEURODEGENERATIVE AND INFLAMMATORY DISEASES | ENCEFA (FR) | 2021-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210087290-A1 | COMPOUNDS WHICH SPECIFICALLY BIND TO CD38 FOR USE IN THE TREATMENT OF NEURODEGENERATIVE AND INFLAMMATORY DISEASES | CD38, TRPC1, TRPC4 | CASP3 2576/4885SENP8 2120/4885SENP7 2586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.