Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 5/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 3/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26976334 | 0.96 | ALOX15 (0.59) | ALOX15CYP3A4HSD17B10ALDH1A1TDP1 | |
| SCHEMBL5842729 | 0.85 | ALOX15 (0.55) | ALOX15CYP3A4HSD17B10ALDH1A1TDP1 | |
| SCHEMBL5845352 | 0.85 | ALOX15 (0.55) | ALOX15CYP3A4HSD17B10ALDH1A1TDP1 | |
| SCHEMBL5843910 | 0.82 | ALOX15 (0.57) | ALOX15CYP3A4HSD17B10ALDH1A1TDP1 | |
| SCHEMBL23137330 | 0.82 | ALOX15 (0.76) | ALOX15CYP3A4HSD17B10ALDH1A1TDP1 | |
| SCHEMBL5845306 | 0.82 | HSD17B10 (0.52) | ALOX15CYP3A4HSD17B10ALDH1A1TDP1 | |
| SCHEMBL5845543 | 0.82 | CYP3A4 (0.52) | ALOX15CYP3A4HSD17B10ALDH1A1TDP1 | |
| SCHEMBL5845314 | 0.82 | CYP3A4 (0.52) | ALOX15CYP3A4HSD17B10ALDH1A1TDP1 | |
| SCHEMBL5844951 | 0.82 | CYP3A4 (0.52) | ALOX15CYP3A4HSD17B10ALDH1A1TDP1 | |
| SCHEMBL8243139 | 0.81 | ALDH1A1 (0.74) | ALOX15CYP3A4HSD17B10ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11858814-B2 | Reticulation of macromolecules into crystalline networks | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-01-02 | — | — | US | disclosed |
| US-11858814-B2 | Reticulation of macromolecules into crystalline networks | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-01-02 | — | — | US | disclosed |
| US-20210087064-A1 | RETICULATION OF MACROMOLECULES INTO CRYSTALLINE NETWORKS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2021-03-25 | — | — | US | disclosed |