Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 9/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 7/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.40 |
| ▸ | ATF1 | P18846 | 2/20 | 0.40 |
| ▸ | JUN | P05412 | 2/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.40 |
| ▸ | RELA | Q04206 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2307609 | 0.86 | ATF1 (0.43) | KDM4ENR1H2NR1H3CNR2NFKB1 | |
| SCHEMBL16562336 | 0.86 | ATF1 (0.44) | CNR2NFKB1ATF1JUNNFKB2 | |
| Ammonia Solution, Strong SCHEMBL2309304 | 0.83 | PTPN11 (0.34) | KDM4ENR1H2NR1H3NFKB1ATF1 | |
| SCHEMBL2312752 | 0.80 | P2RY1 (0.40) | ALDH1A1 | |
| SCHEMBL2308710 | 0.80 | NR1H2 (0.40) | NR1H2NR1H3NFKB1ATF1 | |
| SCHEMBL2308717 | 0.79 | NR1H2 (0.42) | ACACBNR1H2NR1H3NFKB1ATF1 | |
| SCHEMBL2359132 | 0.79 | ATF1 (0.32) | NR1H2NR1H3NFKB1ATF1 | |
| SCHEMBL13219714 | 0.79 | OPRL1 (0.34) | NR1H2NR1H3NFKB1ATF1 | |
| SCHEMBL807915 | 0.78 | NR1H2 (0.35) | KDM4ENR1H2NR1H3NFKB1ATF1 | |
| SCHEMBL3039212 | 0.78 | NR1H2 (0.33) | NR1H2NR1H3CNR2NFKB1ATF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3095780-A1 | PESTICIDAL ARYLPYRROLIDINES | Bayer Intellectual Property GmbH (DE) | 2016-11-23 | — | — | EP | disclosed |
| EP-3095780-A1 | PESTICIDAL ARYLPYRROLIDINES | Bayer Intellectual Property GmbH (DE) | 2016-11-23 | — | — | EP | disclosed |
| US-9271499-B2 | Pesticidal arylpyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-03-01 | — | — | US | disclosed |
| US-9271499-B2 | Pesticidal arylpyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-03-01 | — | — | US | disclosed |
| US-9271499-B2 | Pesticidal arylpyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-03-01 | — | — | US | disclosed |
| US-9266830-B2 | Pesticidal arylpyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-02-23 | — | — | US | disclosed |
| US-9266830-B2 | Pesticidal arylpyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-02-23 | — | — | US | disclosed |
| US-9266830-B2 | Pesticidal arylpyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-02-23 | — | — | US | disclosed |
| US-20150073139-A1 | Pesticidal Arylpyrrolidines | BAYER CROPSCIENCE AG (DE) | 2015-03-12 | — | — | US | disclosed |
| US-20150073139-A1 | Pesticidal Arylpyrrolidines | BAYER CROPSCIENCE AG (DE) | 2015-03-12 | — | — | US | disclosed |
| US-20130310408-A1 | Pesticidal Arylpyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-11-21 | — | — | US | disclosed |
| US-20130310408-A1 | Pesticidal Arylpyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-11-21 | — | — | US | disclosed |
| US-8450483-B2 | Pesticidal arylpyrrolidines | BAYER CROPSCIENCE AG (DE) | 2013-05-28 | — | — | US | disclosed |
| US-8450483-B2 | Pesticidal arylpyrrolidines | BAYER CROPSCIENCE AG (DE) | 2013-05-28 | — | — | US | disclosed |
| US-8450483-B2 | Pesticidal arylpyrrolidines | BAYER CROPSCIENCE AG (DE) | 2013-05-28 | — | — | US | disclosed |
| EP-2349994-A1 | PESTICIDAL (HETERO) ARYLPYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2011-08-03 | — | — | EP | disclosed |
| US-20100216792-A1 | Pesticidal arylpyrrolidines | BAYER CROPSCIENCE AG (DE) | 2010-08-26 | — | — | US | disclosed |
| US-20100216792-A1 | Pesticidal arylpyrrolidines | BAYER CROPSCIENCE AG (DE) | 2010-08-26 | — | — | US | disclosed |
| US-20100216792-A1 | Pesticidal arylpyrrolidines | BAYER CROPSCIENCE AG (DE) | 2010-08-26 | — | — | US | disclosed |
| WO-2010043315-A1 | PESTICIDAL (HETERO) ARYLPYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2010-04-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216792-A1 | Pesticidal arylpyrrolidines | DDT, AADAC, AHR | KDM4E 262/4885ACACB 2402/4885NR1H2 3208/4885 |
| US-20150073139-A1 | Pesticidal Arylpyrrolidines | DDT, ACHE, QDPR | KDM4E 132/4885ACACB 2084/4885NR1H2 3663/4885 |
| US-20130310408-A1 | Pesticidal Arylpyrrolidines | DDT, ACHE, QDPR | KDM4E 132/4885ACACB 2084/4885NR1H2 3663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.