Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 3/20 | 0.31 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13519621 | 1.00 | MAOB (0.33) | MAOBDRD2DRD3KMT2ALTA4H | |
| SCHEMBL12433996 | 0.93 | DRD2 (0.35) | MAOBDRD2DRD3KMT2ALTA4H | |
| SCHEMBL12432614 | 0.93 | DRD2 (0.34) | MAOBDRD2DRD3KMT2ALTA4H | |
| SCHEMBL2315661 | 0.93 | DRD2 (0.34) | MAOBDRD2DRD3KMT2ALTA4H | |
| SCHEMBL2314393 | 0.93 | MAOB (0.39) | MAOBDRD2DRD3KMT2ALTA4H | |
| SCHEMBL12433997 | 0.93 | MAOB (0.39) | MAOBDRD2DRD3KMT2ALTA4H | |
| SCHEMBL2314928 | 0.91 | MAOB (0.31) | MAOBLTA4H | |
| SCHEMBL12432832 | 0.91 | DRD2 (0.32) | MAOBDRD2DRD3KMT2ALTA4H | |
| SCHEMBL2313971 | 0.91 | DRD2 (0.32) | MAOBDRD2DRD3KMT2ALTA4H | |
| SCHEMBL14135130 | 0.91 | HTR7 (0.35) | MAOBDRD2DRD3KMT2ALTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125782-B1 | ARYL CARBOXYLIC ACID CYCLOHEXYL AMIDE DERIVATIVES | NOVARTIS AG (CH) | 2011-08-03 | — | — | EP | disclosed |