Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553597 | 0.82 | HDAC6 (0.39) | HDAC6HDAC1HDAC2PDK2CA14 | |
| SCHEMBL10260946 | 0.79 | HDAC6 (0.40) | HDAC6HDAC1HDAC2PDK2CA14 | |
| SCHEMBL21880331 | 0.79 | HDAC6 (0.37) | HDAC6HDAC1HDAC2PDK2CA14 | |
| SCHEMBL381146 | 0.78 | HDAC6 (0.39) | HDAC6HDAC1HDAC2PDK2CA14 | |
| SCHEMBL8383402 | 0.77 | HDAC6 (0.38) | HDAC6HDAC1HDAC2PDK2CA14 | |
| Succinic Acid SCHEMBL28315096 | 0.77 | PHF8 (0.39) | HDAC6HDAC1HDAC2PDK2CA14 | |
| SCHEMBL8383405 | 0.77 | HDAC6 (0.38) | HDAC6HDAC1HDAC2PDK2CA14 | |
| SCHEMBL3293559 | 0.76 | HDAC6 (0.40) | HDAC6HDAC1HDAC2PDK2CA14 | |
| SCHEMBL30696954 | 0.76 | HDAC6 (0.33) | HDAC6HDAC1HDAC2PDK2CA14 | |
| SCHEMBL12310814 | 0.75 | HDAC6 (0.37) | HDAC6HDAC1HDAC2PDK2CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021052892-A1 | PIPERIDINYL AMINE COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASE | F. HOFFMANN-LA ROCHE AG (CH) | 2021-03-25 | — | — | WO | disclosed |