SCHEMBL8383402

SCHEMBL8383402

CN(CCC([NH])=O)C(=O)OC(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 2/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC2 Q92769 1/20 0.38
CA14 Q9ULX7 3/20 0.34
PDK2 Q15119 1/20 0.34
GBA1 P04062 1/20 0.33
HTR2C P28335 1/20 0.32
SLC6A4 P31645 1/20 0.32
FPR3 P25089 1/20 0.31
FPR2 P25090 1/20 0.31
CA12 O43570 2/20 0.31
CA1 P00915 2/20 0.31
CA7 P43166 1/20 0.31
CACNA1G O43497 1/20 0.31
CACNA1B Q00975 1/20 0.31
CACNA1C Q13936 1/20 0.31
CA2 P00918 1/20 0.31
AAK1 Q2M2I8 1/20 0.31
CTSK P43235 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10260946 0.83 HDAC6 (0.40) HDAC6HDAC1HDAC2CA14PDK2
SCHEMBL8553597 0.82 HDAC6 (0.39) HDAC6HDAC1HDAC2CA14PDK2
SCHEMBL381146 0.82 HDAC6 (0.39) HDAC6HDAC1HDAC2CA14PDK2
Succinic Acid SCHEMBL28315096 0.81 PHF8 (0.39) HDAC6HDAC1HDAC2CA14PDK2
SCHEMBL8383405 0.81 HDAC6 (0.38) HDAC6HDAC1HDAC2CA14PDK2
SCHEMBL8518995 0.80 HDAC6 (0.36) HDAC6HDAC1HDAC2CA14PDK2
SCHEMBL5884651 0.79 MEN1 (0.52) HDAC6HDAC1HDAC2CA14PDK2
SCHEMBL12310814 0.79 HDAC6 (0.37) HDAC6HDAC1HDAC2CA14PDK2
SCHEMBL21880331 0.79 HDAC6 (0.37) HDAC6HDAC1HDAC2CA14PDK2
SCHEMBL28315095 0.79 HDAC6 (0.37) HDAC6HDAC1HDAC2CA14PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5861429-A MITICIDES AND ANTHELMINTICS SANKYO COMPANY, LIMITED (JP) 1999-01-19 US disclosed