SCHEMBL23139656

SCHEMBL23139656

CC(C)(C)c1nc(Nc2cccnc2)nc(Nc2cccnc2)n1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.45
RAD52 P43351 1/20 0.45
NPC1 O15118 4/20 0.44
RAB9A P51151 4/20 0.44
KIF11 P52732 1/20 0.44
HTT P42858 2/20 0.43
ALDH1A1 P00352 2/20 0.43
POLB P06746 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
MAPT P10636 3/20 0.42
NPSR1 Q6W5P4 2/20 0.42
MEN1 O00255 2/20 0.42
NAMPT P43490 1/20 0.42
ADRA2A P08913 2/20 0.41
ADRA2B P18089 2/20 0.41
ADRA2C P18825 2/20 0.41
MAPK1 P28482 2/20 0.41
CLK1 P49759 1/20 0.41
CCNK O75909 1/20 0.41
CCNA2 P20248 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23139602 0.82 NPC1 (0.57) KMT2ANPC1RAB9AALDH1A1MAPT
SCHEMBL23666278 0.80 KCNH3 (0.45) KMT2ARAD52NPC1RAB9AMAPT
SCHEMBL9425993 0.79 NPC1 (0.44) KMT2ARAD52NPC1RAB9AKIF11
SCHEMBL28121637 0.78 NPC1 (0.53) KMT2ANPC1RAB9AHTTALDH1A1
SCHEMBL23786279 0.76 KCNH3 (0.46) KMT2ARAD52NPC1RAB9AKIF11
SCHEMBL4544818 0.75 ABL1 (0.62) NPC1RAB9AKIF11HTTALDH1A1
SCHEMBL29793056 0.74 KIF11 (0.60) KMT2ARAD52NPC1RAB9AKIF11
SCHEMBL1368828 0.74 KIF11 (0.60) KMT2ARAD52NPC1RAB9AKIF11
SCHEMBL16473180 0.74 NAMPT (0.61) KMT2ANPC1RAB9AKIF11HTT
SCHEMBL1319589 0.73 SYK (0.51) KMT2ARAD52POLBMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12019371-B2 Photosensitive composition, film, color filter, solid-state imaging element, and image display device FUJIFILM CORPORATION (JP) 2024-06-25 US disclosed
US-12019371-B2 Photosensitive composition, film, color filter, solid-state imaging element, and image display device FUJIFILM CORPORATION (JP) 2024-06-25 US disclosed
US-20210088902-A1 PHOTOSENSITIVE COMPOSITION, FILM, COLOR FILTER, SOLID-STATE IMAGING ELEMENT, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2021-03-25 US disclosed