Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTPS1 | P17812 | 17/20 | 0.53 |
| ▸ | CTPS2 | Q9NRF8 | 3/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24088748 | 0.82 | CTPS1 (0.55) | CTPS1CTPS2 | |
| SCHEMBL21076844 | 0.79 | CTPS1 (0.65) | CTPS1CTPS2 | |
| SCHEMBL21044575 | 0.79 | CTPS1 (0.60) | CTPS1 | |
| SCHEMBL21044274 | 0.74 | CTPS1 (0.59) | CTPS1 | |
| SCHEMBL24088635 | 0.74 | CTPS1 (0.42) | CTPS1CTPS2 | |
| SCHEMBL21044371 | 0.74 | CTPS1 (0.55) | CTPS1 | |
| SCHEMBL24088718 | 0.73 | APLNR (0.49) | CTPS1 | |
| SCHEMBL22490834 | 0.72 | CTPS1 (0.51) | CTPS1CTPS2 | |
| SCHEMBL22490778 | 0.72 | CTPS1 (0.48) | CTPS1CTPS2 | |
| SCHEMBL19139790 | 0.72 | ALDH1A1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022087634-A1 | CTPS1 INHIBITORS AND USES THEREOF | NIMBUS CLOTHO, INC. (US) | 2022-04-28 | — | — | WO | disclosed |
| WO-2021053402-A2 | COMPOUNDS | STEP PHARMA S.A.S. (FR) | 2021-03-25 | — | — | WO | disclosed |