SCHEMBL2314101

SCHEMBL2314101

Cc1cccc(-c2ccn(N)n2)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 5/20 0.53
NPC1 O15118 4/20 0.53
ALDH1A1 P00352 4/20 0.53
L3MBTL1 Q9Y468 3/20 0.53
NFKB1 P19838 2/20 0.53
NFKB2 Q00653 2/20 0.53
RELA Q04206 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
KDM4E B2RXH2 1/20 0.46
IDO1 P14902 1/20 0.45
METAP2 P50579 1/20 0.45
XDH P47989 1/20 0.43
LMNA P02545 1/20 0.42
MAPT P10636 2/20 0.42
KMT2A Q03164 4/20 0.41
MEN1 O00255 1/20 0.41
TLR8 Q9NR97 1/20 0.40
TP53 P04637 1/20 0.40
ATP4A P20648 1/20 0.40
ATP4B P51164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2629317 0.81 KMT2A (0.62) RAB9ANPC1ALDH1A1L3MBTL1NFKB1
SCHEMBL28073914 0.79 GAA (0.46) RAB9ANPC1L3MBTL1KDM4EIDO1
SCHEMBL20697832 0.79 KMT2A (0.58) RAB9ANPC1ALDH1A1L3MBTL1NFKB1
SCHEMBL28073870 0.79 KDM4E (0.47) KDM4EIDO1MAPTKMT2AMEN1
SCHEMBL28073890 0.79 HSD17B2 (0.52) METAP2ATP4AATP4B
SCHEMBL24776538 0.77 RAB9A (0.48) RAB9ANPC1ALDH1A1L3MBTL1NFKB1
SCHEMBL17397928 0.77 KMT2A (0.59) RAB9AALDH1A1L3MBTL1SMN1; SMN2KDM4E
SCHEMBL27012631 0.76 NPC1 (0.47) RAB9ANPC1ALDH1A1L3MBTL1NFKB1
SCHEMBL26251784 0.76 NPC1 (0.47) RAB9ANPC1ALDH1A1L3MBTL1NFKB1
SCHEMBL23986239 0.76 RAB9A (0.47) RAB9ANPC1ALDH1A1L3MBTL1NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11273115-B2 Hair dyeing method using a dye composition and an oxidizing composition, said compositions comprising a scleroglucan gum L'OREAL (FR) 2022-03-15 US disclosed
US-20210113449-A1 HAIR DYEING METHOD USING A DYE COMPOSITION AND AN OXIDIZING COMPOSITION, SAID COMPOSITIONS COMPRISING A SCLEROGLUCAN GUM L'OREAL (FR) 2021-04-22 US disclosed
EP-1831315-B1 DYES THAT ARE SOLUBLE IN ORGANIC SOLVENTS BASF SE (DE) 2011-08-03 EP disclosed
US-7470780-B2 Dyes that are soluble in organic solvents CIBA SPECIALTY CHEMICALS CORPORATION (US) 2008-12-30 US disclosed
US-20080103313-A1 Dyes that are Soluble in Organic Solvents CIBA SPECIALTY CHEMICALS CORP. 2008-05-01 US disclosed
EP-1831315-A2 DYES THAT ARE SOLUBLE IN ORGANIC SOLVENTS CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) 2007-09-12 EP disclosed
WO-2006069928-A2 DYES THAT ARE SOLUBLE IN ORGANIC SOLVENTS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-07-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11273115-B2 Hair dyeing method using a dye composition and an oxidizing composition, said compositions comprising a scleroglucan gum OGG1, ALPG, KRT18 RAB9A 4604/4885NPC1 4820/4885ALDH1A1 487/4885
US-20080103313-A1 Dyes that are Soluble in Organic Solvents CAT, TYR, KIT RAB9A 3468/4885NPC1 1290/4885ALDH1A1 36/4885
US-20210113449-A1 HAIR DYEING METHOD USING A DYE COMPOSITION AND AN OXIDIZING COMPOSITION, SAID COMPOSITIONS COMPRISING A SCLEROGLUCAN GUM OGG1, ALPG, KRT18 RAB9A 4604/4885NPC1 4820/4885ALDH1A1 487/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.